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6h82
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6h82 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the archaeal extremophilic internal membrane containing Haloarcula hispanica icosahedral virus 2 (HHIV-2) at 3.78 Angstroms resolution.== | |
| + | <SX load='6h82' size='340' side='right' viewer='molstar' caption='[[6h82]], [[Resolution|resolution]] 3.78Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6h82]] is a 32 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_hispanica_icosahedral_virus_2 Haloarcula hispanica icosahedral virus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H82 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6H82 FirstGlance]. <br> | ||
| + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6h82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h82 OCA], [http://pdbe.org/6h82 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h82 RCSB], [http://www.ebi.ac.uk/pdbsum/6h82 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h82 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The vertical double beta-barrel major capsid protein (MCP) fold, fingerprint of the PRD1-adeno viral lineage, is widespread in many viruses infecting organisms across the three domains of life. The discovery of PRD1-like viruses with two MCPs challenged the known assembly principles. Here, we present the cryo-electron microscopy (cryo-EM) structures of the archaeal, halophilic, internal membrane-containing Haloarcula californiae icosahedral virus 1 (HCIV-1) and Haloarcula hispanica icosahedral virus 2 (HHIV-2) at 3.7 and 3.8 A resolution, respectively. Our structures reveal proteins located beneath the morphologically distinct two- and three-tower capsomers and homopentameric membrane proteins at the vertices that orchestrate the positioning of pre-formed vertical single beta-barrel MCP heterodimers. The cryo-EM based structures together with the proteomics data provide insights into the assembly mechanism of this type of viruses and into those with membrane-less double beta-barrel MCPs. | ||
| - | + | Structural basis for assembly of vertical single beta-barrel viruses.,Santos-Perez I, Charro D, Gil-Carton D, Azkargorta M, Elortza F, Bamford DH, Oksanen HM, Abrescia NGA Nat Commun. 2019 Mar 12;10(1):1184. doi: 10.1038/s41467-019-08927-2. PMID:30862777<ref>PMID:30862777</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6h82" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Haloarcula hispanica icosahedral virus 2]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Abrescia, N G]] | ||
| + | [[Category: Charro, D]] | ||
| + | [[Category: Santos-Perez, I]] | ||
| + | [[Category: Archaeal]] | ||
| + | [[Category: Membrane-containing]] | ||
| + | [[Category: Quasi-atomic resolution]] | ||
| + | [[Category: Single vertical beta-barrel virus]] | ||
| + | [[Category: Virus]] | ||
Current revision
Cryo-EM structure of the archaeal extremophilic internal membrane containing Haloarcula hispanica icosahedral virus 2 (HHIV-2) at 3.78 Angstroms resolution.
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