This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6r9b
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of bacterial RNAP with a DNA mimic protein Ocr from T7 phage== | |
| - | + | <SX load='6r9b' size='340' side='right' viewer='molstar' caption='[[6r9b]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6r9b]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R9B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6R9B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6r9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r9b OCA], [http://pdbe.org/6r9b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r9b RCSB], [http://www.ebi.ac.uk/pdbsum/6r9b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r9b ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/F4NQ47_ECOLX F4NQ47_ECOLX]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366][SAAS:SAAS00387808] [[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/RPOC_ECOLI RPOC_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322] [[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321] | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: DNA-directed RNA polymerase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ye, F Z]] | ||
| + | [[Category: Zhang, X D]] | ||
| + | [[Category: Bacteriophage t7]] | ||
| + | [[Category: Ocr]] | ||
| + | [[Category: Rna polymerase]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Transcription inhibition]] | ||
Current revision
Cryo-EM structure of bacterial RNAP with a DNA mimic protein Ocr from T7 phage
| |||||||||
