Nucleoside triphosphatase

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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='4a5a' size='340' side='right' caption='Caption for this structure' scene=''>
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10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
== Function ==
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'''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase)
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'''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase) is responsible for degradation of nucleotides to their monophosphate form. NTPase is found in mammals and in pathogenic microbes. In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides. The function of NTPase in pathogens is still unknown<ref>PMID:21638687</ref>.
== Disease ==
== Disease ==
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**[[6dt3]] - Nudi - ''Klebsiella pneumoniae'' <br />
**[[6dt3]] - Nudi - ''Klebsiella pneumoniae'' <br />
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**[[3oga]], [[3n77]] - Nudi - ''Salmonella enterica'' <br />
*Nucleoside triphosphatase cancer-related
*Nucleoside triphosphatase cancer-related
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**[[3s86]] - NTPase - ''Thermotoga maritima'' <br />
**[[3s86]] - NTPase - ''Thermotoga maritima'' <br />
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**[[3agr]] - NTPase - ''Neospora caninum'' <br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:37, 12 May 2020

Caption for this structure

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3D structures of nucleoside triphosphatase

Updated on 12-May-2020

References

  1. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

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Alexander Berchansky, Michal Harel, Joel L. Sussman

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