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User:Dora Bonadio/Sandbox 1
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| - | ==<!-- Your Heading Here --> SARS-Cov-2 main protease== | + | ==<!-- Your Heading Here --> SARS-Cov-2 main protease (Mpro)== |
<StructureSection load='6Y2E' size='340' side='right' caption='6Y2E' scene=''> | <StructureSection load='6Y2E' size='340' side='right' caption='6Y2E' scene=''> | ||
| - | This is a default text for your page '''Dora Bonadio/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | + | <!-- This is a default text for your page '''Dora Bonadio/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. --> |
| + | The Mpro protease (also known as 3CLpro), is a viral non structural protein from the virus SARS-CoV-2 (1), responsible for a major outbreak of the disease called COVID-19, declared pandemic by WHO in 11 march 2020 (2). It has an important role in virus replication, as it’s responsible for cleavage of the polyproteins of the virus, alongside with papain-like protease(s) (3). | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
Revision as of 02:20, 16 May 2020
SARS-Cov-2 main protease (Mpro)
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
