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5i6u

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==The crystal structure of PI3Kdelta with compound 32==
==The crystal structure of PI3Kdelta with compound 32==
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<StructureSection load='5i6u' size='340' side='right' caption='[[5i6u]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
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<StructureSection load='5i6u' size='340' side='right'caption='[[5i6u]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5i6u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I6U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I6U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5i6u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I6U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5I6U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=68R:2-[(1S)-1-({6-AMINO-5-[(1H-PYRAZOL-4-YL)ETHYNYL]PYRIMIDIN-4-YL}AMINO)ETHYL]-5-CHLORO-3-PHENYLQUINAZOLIN-4(3H)-ONE'>68R</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=68R:2-[(1S)-1-({6-AMINO-5-[(1H-PYRAZOL-4-YL)ETHYNYL]PYRIMIDIN-4-YL}AMINO)ETHYL]-5-CHLORO-3-PHENYLQUINAZOLIN-4(3H)-ONE'>68R</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i4u|5i4u]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i4u|5i4u]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pik3cd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i6u OCA], [http://pdbe.org/5i6u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i6u RCSB], [http://www.ebi.ac.uk/pdbsum/5i6u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i6u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5i6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i6u OCA], [http://pdbe.org/5i6u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i6u RCSB], [http://www.ebi.ac.uk/pdbsum/5i6u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i6u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Somoza, J R]]
[[Category: Somoza, J R]]

Revision as of 07:06, 3 June 2020

The crystal structure of PI3Kdelta with compound 32

PDB ID 5i6u

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