Antibody 3D structures

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Revision as of 08:38, 11 June 2020 (edit) Joel L. Sussman (Talk | contribs) ← Previous diff		Revision as of 08:42, 11 June 2020 (edit) (undo) Joel L. Sussman (Talk | contribs) Next diff →
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	**[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br />		**[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br />
	**[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br />		**[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br />
		+
	*Human Fab: protein complex		*Human Fab: protein complex
Line 391:		Line 392:
	**[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br />		**[[4r4n]], [[4r4f]] - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide<br />
	**[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br />		**[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br />
		+
	*Mouse Fab: protein higher complexes		*Mouse Fab: protein higher complexes
Line 404:		Line 406:
	**[[6jmq]], [[6jmr]] – mFab + large neutral amino acid transporter + 4f2 cell-surface antigen<br />		**[[6jmq]], [[6jmr]] – mFab + large neutral amino acid transporter + 4f2 cell-surface antigen<br />
	**[[6qno]] - mFab + guanine nucleotide-binding protein + transducin + rhodopsin – Cryo EM<br />		**[[6qno]] - mFab + guanine nucleotide-binding protein + transducin + rhodopsin – Cryo EM<br />
		+
	*Full Immunoglobulin		*Full Immunoglobulin
Line 418:		Line 421:
	**[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br />		**[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br />
	**[[1fp5]] - hFc IgE C ε 3-C ε 4<br />		**[[1fp5]] - hFc IgE C ε 3-C ε 4<br />
		+
	*Fv Fragments		*Fv Fragments
Line 427:		Line 431:
	**[[1qle]] - mFv + cytochrome c oxidase<br />		**[[1qle]] - mFv + cytochrome c oxidase<br />
	**[[6oik]] - mFv + AChR + guanine nucleotide-binding protein + transducin – Cryo EM<br />		**[[6oik]] - mFv + AChR + guanine nucleotide-binding protein + transducin – Cryo EM<br />
		+
	* Single chain variable fragment (scFv)		* Single chain variable fragment (scFv)
Line 436:		Line 441:
	**[[1p4i]] – mscFv (mutant)<br />		**[[1p4i]] – mscFv (mutant)<br />
	**[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br />		**[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br />
		+
	* Single chain variable fragment complex		* Single chain variable fragment complex
Line 466:		Line 472:
	**[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br />		**[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br />
	**[[5d9q]] – hscFv + antibody + gp120 + gp40<br />		**[[5d9q]] – hscFv + antibody + gp120 + gp40<br />
		+
	* Single chain variable fragment complex with small molecule		* Single chain variable fragment complex with small molecule
Line 476:		Line 483:
	**[[4lar]] – hscFv + dexedrine<br />		**[[4lar]] – hscFv + dexedrine<br />
	**[[4las]] – hscFv + amphetamine derivative<br />		**[[4las]] – hscFv + amphetamine derivative<br />
		+
	* Single chain variable fragment complex with peptide		* Single chain variable fragment complex with peptide
Line 501:		Line 509:
	**[[6itp]], [[6itq]] – cVHH anti-cortisol<br />		**[[6itp]], [[6itq]] – cVHH anti-cortisol<br />
	**[[6t2j]] – syVHH <br />		**[[6t2j]] – syVHH <br />
		+
	*VHH binary complexes		*VHH binary complexes
Line 549:		Line 558:
	**[[6knm]] - cVHH + apelin receptor<br />		**[[6knm]] - cVHH + apelin receptor<br />
	**[[6sc5]], [[6sc6]], [[6sc7]], [[6sc8]], [[6sc9]] – syVHH + RNF31<br />		**[[6sc5]], [[6sc6]], [[6sc7]], [[6sc8]], [[6sc9]] – syVHH + RNF31<br />
		+
	*VHH ternary complexes		*VHH ternary complexes
Line 564:		Line 574:
	**[[6h7o]], [[6ibl]] – cVHH + thioredoxin + adrenergic receptor<br />		**[[6h7o]], [[6ibl]] – cVHH + thioredoxin + adrenergic receptor<br />
		+	}}
	[[Category: Topic Page]]		[[Category: Topic Page]]

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Revision as of 08:42, 11 June 2020

Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
Lama antibodies or nanobodies or camelid or VHH are natural single-domain antibodies containing just the heavy chain.
scFv is a single chain variable fragment in a fusion protein of the variable regions of the heavy and light chains of immunoglobulin.

3D structures of Antibody

Updated on 11-June-2020 {{#tree:id=OrganizedByTopic|openlevels=0|

• Fab

• • 7fab, 1mco, 3na9, 3lrs, 3mme, 3hi5, 1vge, 3nfs, 1ad0, 3w9d, 4nm4, 8fab, 1opg, 4fnl, 4fqh, 6n32, 1aqk, 2hff, 2agj, 3hc0, 3g6a, 3dgg, 3dif, 1b2w, 3eyo, 3eyq, 2aj3, 3fzu, 3aaz, 3gje, 5fhb, 5fha, 5f6i, 5f6h, 5drw, 5d6c, 4py7, 4ptt, 4ob5, 5szf, 5chn, 4lkc, 4hie, 4gxv, 6u85 - hFab - human
    
  • 3naa, 3nab, 3nac, 3ncj, 3o2v, 3hc3, 3hc4 - hFab (mutant)
    
  • 6b0w, 6azx, 5bk5, 5bk3 - hFab anti-circumsporozoite
    
  • 6meg, 6med, 6mee, 6mef - hFab anti-hepacivirus
    
  • 6dzn, 5vz1 - hFab anti-ebola virus
    
  • 6nis - hFab anti-zika virus
    
  • 6phg, 6phh - hFab anti-malaria
    
  • 3i75, 1nqb, 1f4w, 1aif, 1ghf, 2z91, 1ind, 3bkc, 3bkm, 1iy0, 3pp3, 3pp4, 3okm, 6fab, 2hkh, 1ay1, 1nbv, 1qbm, 1bbd, 1dsf, 1gpo, 1mnu, 1igf, 1for, 1k6q, 1bz7, 1dqd, 2ipt, 2iq9, 2iqa, 2w60, 2w9d, 3iu4, 1q9k, 1q9l, 1q9o, 2z4q, 1cl7, 1cr9, 1r24, 1gig, 1uyw, 1cgs, 2cgr, 1q0x, 1ibg, 3eo0, 2op4, 2q76, 2ojz, 2g60, 2dbl, 1dbj, 1dbk, 1dbm, 1dba, 1mrc, 2gcy, 1flr, 1uz6, 1rfd, 1t2q, 1ggb, 1ggc, 1bm3, 2eh7, 2fat, 3cfc, 1fl3, 3cfe, 4j1u, 4gq9, 3qg7, 3rvt, 3s62, 4gay, 5mx3, 5l88, 5i66, 5cma, 5az2, 4z0b, 4qth, 4poz, 5vzr, 5lgh, 5l9d, 5l7x, 5h2b, 4lci, 4k23, 6p79 - mFab – mouse
    
  • 3eot, 2d03, 3esv, 3et9 – mFab (mutant)
    
  • 3iy2, 3iy3, 3iy4, 3iy5, 3iy6, 3iy7 - mFab – Cryo EM
    
  • 1jpt, 3mxv, 2o5x, 1ucb, 1bbj, 1t04, 2fgw, 1fvd, 1fve, 4kuz, 6l8t - hmFab
    
  • 1cqk – mFab MAK33 CH3 domain
    
  • 6a0x - mFab anti-influenza virus
    
  • 6h3h - mFab anti-fullerene
    
  • 6pyc - mFab anti-kappa
    
  • 6pyd - mFab anti-marinobufagenin
    
  • 6idh, 6kdh - mFab anti-photoproduct
    
  • 3mj8, 3r06 – AhFab – Armenian hamster
    
  • 3iy1, 1zan – raFab – rat
    
  • 4k3e, 4k3d – bFab – bovine
    
  • 6e8v – bFab-1
    
  • 6e9g – bFab-2
    
  • 6e9h – bFab-3
    
  • 6e9i – bFab-4
    
  • 6e9k – bFab-5
    
  • 6e9q – bFab-6
    
  • 6e9u – bFab-7
    
  • 4b41, 4m3j – LgFab – Lama glama
    
  • 6df0, 6dez - syFab anti-phosphotyrosine - synthetic
    

• Anti-HIV Fab

• • 1rz7, 1rz8, 1rzf, 1rzg, 1rzi, 3mlj, 3mug, 3qeh, 3ttn, rpi, 3tnm, 4fz8, 4f58, 4f57, 4f5a, 5iie, 5dt1, 5cey, 5cex, 5cck, 5bzw, 5bzd, 4rqq, 5uy3, 4qf1, 6mtr, 6mts - hFab
    
  • 3nz8, 3o6k, 3ntc, 3qeg – mFab
    
  • 5kg9 – hmFab
    
  • 5dd6, 5dd5, 5dd3, 5dd1, 4rfe, 4q2z, 5t4z – rmFab – rhesus macaque
    

• Human Fab: small molecule complex

• • 3o2w - hFab 1e9 (mutant) + transition state analog
    
  • 3oau – hFab 2g12 (mutant) + mannose
    
  • 4ptu, 4hih – hFab + rhamnose
    
  • 1ikf – hFab R45 + cyclosporin
    
  • 3oay, 3oaz, 3ob0, 6msy, 6mub, [[6mu3], 6mnf - hFab 2g12 + glycan
    
  • 6n35, 6n2x, 5i8o - hFab + polysaccharide
    

• Mouse Fab: small molecule complex

• • 3ra7 – mFab + digoxigenin
    
  • 3okd, 3oke, 3okk, 3okl, 3okn, 3oko, 3hzk, 3hzm, 3hzv, 3hzy, 3pho, 3phq, 3hns, 3hnt, 3hnv - mFab + liposaccharide
    
  • 1ine, 1ub5, 1ub6 - mFab + hapten
    
  • 3ls4 – mFab + tetrahydrocannabinol
    
  • 1mfc, 1mfd, 1mfe, 4hgw – mFab + polysaccharide
    
  • 2ntf - mFab RS2-1G9 + lactone analog
    
  • 1riu, 1riv, 1qyg, 1q72 - mFab + cocaine derivative
    
  • 1ynk, 1ynl, 1etz – mFab + sweetener
    
  • 1yef – mFab D2.3 + substrate analog
    
  • 1yeg - mFab D2.3 + product
    
  • 1p7k – mFab + HEPES
    
  • 1q0y – mFab 9B1 + morphine
    
  • 3sy0, 3t65, 3t77, 3t4y, 1q9w, 1f4x, 1f4y, 1mfa, 1mfb - mFab + carbohydrate
    
  • 1mex – mFab 29G12 + benzoic acid derivative
    
  • 1mrd, 1mre, 1mrf – mFab JEL103 + nucleotide
    
  • 1dbb – mFab DB3 + progesterone
    
  • 1igj - mFab 26-10 + digoxin
    
  • 4fab – mFab 4-4-20 + fluorescin
    
  • 1dl7 - mFab MCPC603 + phosphocholine
    
  • 3cfb, 3cfd, 2g2r – mFab + stilbene hapten
    
  • 4kze, 4kzd – mFab + RNA
    
  • 6kdi - mFab anti-photoproduct + DNA
    

• Other Fab: small molecule complex

• • 2jb5, 2jb6 - hmFab + hapten
    
  • 3eyv - hmFab 13G5 (mutant) + hapten
    

• Mouse Fab: peptide complex

• • 3e8u - mFab + BNP peptide
    
  • 2a6d, 2a6i, 2a6j, 2a6k - mFab + peptide
    
  • 3hr5 – mFab + M1prime peptide
    
  • 3eys, 3eyu - mFab + amyloid-β-related peptide
    
  • 3ggw – mFab + carbohydrate-mimetic peptide
    
  • 3cxd, 3dsf, 5x5x – mFab + osteopontin peptide
    
  • 2zpk – mFab + proteinase-activated receptor peptide
    
  • 3ifl, 3ifn, 3ifo, 3ifp - mFab + amyloid peptide
    
  • 2eh8 - mFab + PRES1 peptide
    
  • 2brr – mFab + outer membrane protein peptide
    
  • 1xgy – mFab + rhodopsin peptide
    
  • 1pz5 – mFab SYA/J6 + peptide
    
  • 1a3r – mFab + rhinovirus capsid peptide
    
  • 1cu4 - mFab + prion protein peptide
    
  • 1fpt – mFab + poliovirus peptide
    
  • 1jp5 – mFab + HIV-1 protease peptide
    
  • 1mvu – mFab + glycoprotein
    
  • 2ap2 – mFab + glycoprotein peptide + C-myc peptide
    
  • 1frg, 1him, 1hin, 1ifh - mFab + hemagglutinin peptide
    
  • 1tet – mFab + cholera toxin peptide
    
  • 5epm – mFab + therapotoxin peptide
    
  • 5eor, 5eoq – mFab + protein A27 peptide
    
  • 1i8i, 1i8k – mFab + EGFR peptide
    
  • 1i8k – mFab + EGFR peptide
    
  • 1i8i, 1i8k – mFab + EGFR peptide
    
  • 1i8k – mFab + EGFR peptide
    
  • 4gag, 4gaj – mFab + genome polyprotein peptide
    
  • 5nph – mFab + hepatitis virus peptide
    
  • 5mv4, 5mu0 – mFab + collagen peptide
    

• Human Fab: peptide complex

• • 3h0t - hFab + hepcidin peptide
    
  • 1sm3 - hFab SM3 + peptide
    
  • 5ea0 - hFab 7968 + complement factor peptide
    
  • 4z0x, 4xvj - hFab + HCV E2 peptide
    
  • 3eyf, 4hha – hFab + cytomegalovirus peptide
    
  • 2hfg, 2h9g – hFab + TNF receptor peptide
    
  • 3csy, 6n7j - hFab + Ebola envelope glycoprotein peptide
    
  • 4hs8, 5kzp – hFab + hepatitis virus peptide
    
  • 6b0s, 6azm, 5bk0, 6d11, 6d0x, 6d01 - hFab anti-circumsporozoite + circumsporozoite domain
    
  • 6h06, 6h0e, 6gk7, 6gk8, 5zia, 5zv3 - hFab + Tau peptide
    
  • 6mtp, 6mtt - hFab + HIV peptide
    

• Other Fab: peptide complex

• • 2hh0 – hmFab + prion protein peptide
    
  • 3bky – hmFab + CD20 peptide
    
  • 5dmg – rFab + microtubule-associated protein peptide - rabbit
    
  • 5dd0 – rmFab + peptide
    
  • 4why, 4wht - raFab + hepatitis peptide
    
  • 6df1, 6df2 - syFab anti-phosphotyrosine + phosphotyrosine peptide
    

• Anti-HIV Fab: peptide complex

• • 3egs, 3drt, 3drq, 3dro, 2fx7, 2fx8, 2fx9, 2cmr, 1tzg, 1tjg, 3mnw, 3moa, 3mob, 3mod, 1tjh, 1tji, 1u8h, 1u8i, 1u8j, 1u8k, 1u8l, 1u8m, 1u8n, 1u8o, 1u8p, 1u8q, 1u91, 1u92, 1u93, 1u95, 2f5b, 3go1, 5drz, 4ydv - hFab anti-HIV + gp41 peptide
    
  • 3ghb, 3ghe, 3c2a - hFab anti-HIV + envelope glycoprotein peptide
    
  • 3fn0, 2oqj - hFab + peptide
    
  • 2b0s, 2b1a, 2b1h, 3se8, 3se9, 4jkp, 4jpv, 4jb9 - hFab anti-HIV + glycoprotein gp120 peptide
    
  • 1nak, 2f58, 3f58, 1f58, 1acy, 1qnz - mFab anti-HIV + glycoprotein gp120 peptide
    
  • 1ai1, 1ggi – mFab anti-HIV + V3 peptide
    
  • 3o6l, 3o6m - mFab 11H6H1 anti-HIV + Tat peptide
    
  • 1svz - mFab anti-HIV + HIV-2 protease peptide
    

• Human Fab: protein complex

• • 3pnw – hFab + Tudor domain-containing protein 3
    
  • 3h42 - hFab LDLR + proprotein convertase subtilisin/kexin
    
  • 3nh7 – hFab ABD1556 + bone morphogenetic protein receptor
    
  • 3hi6 – hFab AL-57 + integrin
    
  • 2vxs, 5fhx - hFab + interleukin
    
  • 3b2u, 3b2v – hFab IMC-11F8 + EGFR
    
  • 2r0k, 2r0l – hFab + HGFA
    
  • 3be1, 3n85, 1n8z, 6att - hFab + ERBB-2
    
  • 6j71 - hmFab + ERBB-2
    
  • 3kr3 – hFab + IGF-II
    
  • 3g6d – hFab CNTO607 + IL-13
    
  • 3g6j – hFab + complement C3
    
  • 2wub, 3k2u – hFab 40 + hepatocyte growth factor activator
    
  • 3grw - hFab + fibroblast growth factor receptor
    
  • 6ba5 - hFab + tyrosine protein kinase receptor
    
  • 3bdy, 2qr0, 2fjg, 2fjh, 1cz8, 5fv2, 5fv1 – hFab + VEGF
    
  • 3bqu – hFab 2F5 anti-HIV + mFab 3H6
    
  • 1adq – hFab IGM + igG1 Fc
    
  • 3dvg, 3dvn – hFab igG1 + ubiquitin
    
  • 3bn9 – hFab E2 + membrane-type serine protease
    
  • 2jix – hFab ABT-007 + erythropoietin receptor
    
  • 1za3 - hFab YSD1 + TNF receptor
    
  • 3l95 – hFab + NRR1
    
  • 1uj3, 4dtg – hFab + tissue factor
    
  • 3lev – hFab 2F5 + RNA polymerase sigma factor
    
  • 3ru8, 6mto, 6mtq – hFab + scaffold
    
  • 3skj – hFab + ephrin receptor
    
  • 3sob – hFab + LPR6
    
  • 5kn5 - hFab + protransforming growth factor alpha
    
  • 5c8j – hFab + protein MJ0480
    
  • 4zso – hFab + natural cytotoxicity triggering receptor
    
  • 4rrp - hFab + ASF1P
    
  • 4qci - hFab + platelet factor B
    
  • 4mxv - hFab + lymphotoxin
    
  • 5dmj, 5ihl - hFab + CD40
    
  • 3vg9 – hFab + adenosine receptor
    
  • 3vga – hFab + adenosine receptor (mutant)
    
  • 2qqk, 2qql, 2qqn – hFab + neuropilin
    
  • 2vyr – hFab + MDM4
    
  • 6b0h, 6b0g, 6b0e, 6b0a, 6b08, 6azz - hFab + PFS25
    
  • 6aod, 6hhc - hFab + coagulation factor
    
  • 5oca - hFab + PCSK9
    
  • 5n88 - hFab + SFRS1-interacting protein
    
  • 5bk1, 5bjz - hFab + maltose-binding protein
    
  • 4hj0 - hFab + GIPR
    
  • 4g80, 4g7y, 4g7v - hFab + VSP
    
  • 6cyf – hFab + secretion system protein
    
  • 6cw3 – hFab + histone acetyltransferase
    
  • 6m58 – hFab + serum albumin
    
  • 6mvl – hFab + VISTA
    
  • 6nmr, 6nms, 6nmt, 6nmu, 6nmv – hFab + SIRP-alpha
    
  • 6o39 – hFab + frizzled-5
    
  • 6o3a, 6o3b – hFab + frizzled-7
    
  • 6phb, 6phc, 6phd, 6phf – hFab + PFS25
    
  • 6r0x – hFab + G6B
    
  • 6r2s – hFab + duffy receptor
    
  • 6u8c – hFab + protein G
    
  • 6xxv – hFab + S2_1.2
    

• Human Fab: viral protein complex

• • 6e3h, 6d0u, 5vag, 3gbm, 3gbn, 3lzf, 3fku, 3sdy, 3ztj, 3ztn, 4fp8, 4fqi, 4fqj, 4fqk, 4fql, 4fqr, 4fqv, 4fqy, 4gxu, 4nm8, 5gjt, 5gjs, 5dur, 5c0s, 4yk4, 4py8, 5wko, 5w6g, 5w0d, 5w08, 5v2a, 5umn, 5kaq, 6ml8, 6e56, 4r8w – hFab + Influenza virus hemagglutinin
    
  • 6pzy, 6pzz – hFab + Influenza virus neuraminidase
    
  • 5gzo, 5gzn, 6dfi, 6dfj, 5lcv – hFab + zika polyprotein
    
  • 5hj3, 5fhc – hFab + ebola envelope protein
    
  • 6dzm, 6uye – hFab + ebola spike proteins – Cryo EM
    
  • 6mej, 6meh, 6mei – hFab + hepacivirus glycoprotein
    
  • 5n09, 4utb, 4uta, 4ut9, 4ut6 – hFab + dengue virus envelope protein
    
  • 4c2i – hFab + dengue virus envelope protein - Cryo EM
    
  • 4dag – hFab + metapneumovirus glycoprotein F0
    
  • 6p91, 6p95 – hFab + lassa mammarenavirus glycoprotein
    
  • 6c6z, 4xak - hFab + coronavirus spike protein
    
  • 6z2m - hFab + coronavirus spike protein + nanobody
    
  • 7bwj - hFab + coronavirus receptor RBD
    
  • 6wps, 6wpt - hFab + coronavirus spike protein – Cryo EM
    

• Mouse Fab: protein complex

• • 1tzh, 1tzi - mFab + VEGF
    
  • 1fsk, 5vfy - mFab + pollen allergen
    
  • 3raj – mFab HB7 + CD38
    
  • 6u9s – mFab 5A6 + CD81
    
  • 3o0r, 5gux – mFab + nitric oxide reductase
    
  • 1ahw - mFab 5G9+ tissue factor
    
  • 2w9e, 1tpx, 1tqb, 1tqc – mFAB + major prion protein
    
  • 2oz4 – mFab + intercellular adhesion molecule
    
  • 3eo1 - mFab GC-1008 + transforming growth factor β-3
    
  • 4zxb – mFab 83 + insulin receptor
    
  • 1egj – mFab + cytokine receptor
    
  • 2bdn – mFab + cytokine A2
    
  • 1jrh – mFab + interferon-γ receptor
    
  • 1ob1 – mFab + major merozoite surface protein
    
  • 1qfw – mFab + gonadotropin
    
  • 4cad – mFab + RCE1
    
  • 4m48, 4xpt, 4xph, 4xpg, 4xpf, 4xpb, 4xpa, 4xp9, 4xp6, 4xp5, 4xp4, 4xp1, 4xnx, 4xnu – mFab + dopamine transporter
    
  • 5i75, 5i74, 5i73, 5i71, 5i6z, 5i6x, 6awq, 6awp, 6awo, 6awn, 6w2b, 6w2c – mFab + serotonin transporter
    
  • 6dzv, 6dzw, 6dzy, 6dzz, 6vrh, 6vrk, 6vrl – mFab + serotonin transporter – Cryo EM
    
  • 1yjd – mFab 5.11A1 + CD28
    
  • 1sy6 – mFab OKT3 + CD3
    
  • 5dfv – mFab + CD81
    
  • 4r0l – mFab + CD28
    
  • 4qex, 4k2u – mFab + erythrocyte binding antigen
    
  • 2r9h, 6ad7, 6ad8, 6ada, 6adb, 6adc – mFab + exchange transporter ClCA
    
  • 1rjl – mFab + outer surface protein
    
  • 1mhh – mFab + protein L (mutant)
    
  • 1pg7 – mFab 6A6 + hmFab D3H44
    
  • 2jel – mFab JEL42 + histidine-containing protein
    
  • 1nsn – mFab N10 + nuclease
    
  • 1nfd – mFab H57 + T-cell receptor
    
  • 1igc – mFab MOPC21 + streptococcal protein G
    
  • 1iai – mFab idiotipic + mFab anti-idiotypic
    
  • 2r8s – mFab + RNA
    
  • 2fr4, 1xf2, 1xf3, 1xf4, 1i8m, 1cbv, 6idg – mFab + DNA
    
  • 1mhp, 3q3g, 3qa3 – mFab + integrin
    
  • 3etb – mFab M18 (mutant) + anthrax-protective antigen
    
  • 3f5w, 3pjs, 3efd, 3eff, 2hjf, 2w0f, 4msw, 4uuj – mFab + KcsA K+ channel
    
  • 3stl, 3stz, 4i9w, 5ec2, 5ec1, 5ebw, 5ebm, 5ebl, 5e1a, 6nfu, 6nfv, 6pa0 - mFab + KcsA K+ channel (mutant)
    
  • 1kb5 – mFab + T-cell receptor
    
  • 4i18 – mFab + pro-lactin receptor
    
  • 1uwx – mFab + protein G prime
    
  • 4ckd – mFab + β-galactosidase
    
  • 5tih – mFab + cysteine-rich protective antigen
    
  • 5t5n, 4rdq – mFab + bestrophin
    
  • 5e94 – mFab + glucagon-like receptor
    
  • 5e8d – mFab + proepiregulin
    
  • 5fb8 - mFab + interleukin
    
  • 5d96, 5d93 - mFab + sulfhydryl oxidase
    
  • 4ybq – mFab + fructose transporter
    
  • 4xzu - mFab + coagulation factor
    
  • 4u6h - mFab + virion membrane protein M25
    
  • 4r9y, 4r97 - mFab + platelet factor 4
    
  • 4qww - mFab + acetylcholinesterase
    
  • 4qti – mFab + urokinase-type plasminogen activator
    
  • 4pp2, 5vco – mFab + peptidase
    
  • 4p3d, 4p3c – mFab + metalloproteinase 14
    
  • 4ong, 4onf - mFab + amyloid-β A4 protein
    
  • 4oii - mFab + NS1
    
  • 5ldn – mFab + hexon C5
    
  • 5ldn – mFab + MIG-C4
    

• Mouse Fab: viral protein complex

• • 6a0z, 1eo8, 1ken, 4mhh, 4mhj, 6n5b, 6n5d - mFab anti-influenza virus hemagglutinin
    
  • 4qnp, 1nca, 1ncb, 1ncc, 1ncd – mFab + influenza neuraminidase
    
  • 1rvf – mFab 17-IA + intact rhinovirus
    
  • 3j3o, 3j3p- mFab + poliovirus proteins – cryoEM
    
  • 6mui, 6mw9, 6mwc, 6mwv, 6mwx - mFab + equine encephalitis virus proteins – cryoEM
    
  • 6j5g, 6j5f - mFab + tick-borne encephalitis virus protein
    
  • 6j5d - mFab + louping ILL virus protein – cryoEM
    
  • 5kvg, 5kvf, 5kve, 5kvd, 5jhl – mFab + zika envelope DIII
    
  • 3ve0 - mFab + Ebola envelope glycoprotein
    
  • 5y9t, 5y9c, 5y9f – mFab + papilloma virus capsid protein
    
  • 4l5f – mFab + dengue virus envelope protein
    
  • 5zud, 5zuf – mFab + enterovirus caspid proteins – Cryo EM
    
  • 6tys – mFab + nipa virus fusion protein – Cryo EM
    
  • 3fmg – mFab + rotavirus glycoprotein VP7
    
  • 3ixx, 3ixy - mFab E53 + envelope glycoprotein + West Nile virus peptide
    

• Anti-HIV Fab: protein complex

• • 3mac, 3ma9 – hFab anti-HIV 8062 + transmembrane glycoprotein
    
  • 3idx, 3idy, 2ny7, 4jpw, 4lsp, 4lsq, 4lsr, 4lss, 4lst, 4lsu, 4lsv, 5te4, 5fyl, 5f9w, 5f96, 5f6j, 4ywg, 4ye4, 4ydl, 4ydk, 4ydj, 4ydi, 4yc2, 4ybl, 4s1s, 4s1r, 4s1q, 4rwy, 4rfn, 5w4l, 5uwe - hFab anti-HIV + gp120 core
    
  • 5v7j, 4j6r - hFab anti-HIV + gp160
    
  • 6pwu - hFab anti-HIV + gp160 – Cryo EM
    
  • 4xnz, 4xny, 4xmp - hFab anti-HIV + gp41
    
  • 6orn, 6oro, 6orp, 6orq - hFab anti-HIV + gp41 + gp120
    
  • 6ulc - hFab anti-HIV + gp41 + gp120 – Cryo EM
    
  • 6vpx - hFab anti-HIV + gp41 + gp120 + MPER peptide – Cryo EM
    
  • 5tfw, 5t85, 5t80, 5t6l, 5t5b, 5t29 - hFab anti-HIV + T117V2
    
  • 2x7l – hFab anti-HIV + HIV REV
    
  • 1afv – mFab anti-HIV + capsid protein C
    

• Other Fab: protein complex

• • 3ld8, 3ldb – AhFab + bifunctional arginine demethylase
    
  • 3mj9 – AhFab HL4E10 + JAML
    
  • 3r08 - AhFab 2C11 + CD3ε
    
  • 1jps - hmFab D3H44 + tissue factor
    
  • 5f3h, 5f3b - hmFab + growth factor 8
    
  • 1pkq – hmFab 8-18C5 + myelin glycoprotein
    
  • 2b2x – rFab AQC2 + integrin
    
  • 4ht1 – rFab + TNF ligand 12
    
  • 6cf2 – rFab + REV
    
  • 6p65 – rFab + HIV protein – Cryo EM
    
  • 6osh, 6osv – rFab + ROR2
    
  • 2r56 – bFab igE + β-lactoglobulin
    
  • 1g6v – bFab + carbonic anhydrase
    
  • 4hgk – Fab + albumin – shark
    
  • 4n9g - rmFab + scaffold
    
  • 6mqc, 6mqe, 6mqm, 6mqr, 6mqs, 6n16 - rmFab + HIV fusion peptide
    
  • 6tyb - rmFab + SIV gp160
    
  • 6oor – raFab + β-2-microglobulin + CD1D
    
  • 6h5n – raFab + malaria protein
    
  • 6qig – raFab + ADAMTS-13
    
  • 6p60 - Fab + HIV fusion peptide - platytthini
    
  • 6i8s - Fab + plasminogen activator inhibitor – Escherichia coli
    
  • 6pis – Fab + TRAAK – Cricetulus migratorius
    

• Human Fab: protein higher complexes

• • 2wuc - hFab 40 + hepatocyte growth factor activator + inhibitor
    
  • 3d85 - hFab 7G10 + IL-12 + IL-23
    
  • 4xwo - hFab + ATPase GET3 + Sec22
    
  • 4xvu - hFab + ATPase GET3 + NYV1
    
  • 4xtr - hFab + ATPase GET3 + PEP12P peptide
    
  • 4xmn - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85
    
  • 4xmm - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85 + SEH1
    
  • 4mxw - hFab + TNFR-III + lymphotoxin
    
  • 3bt2 – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin
    
  • 3gjf, 3hae – hFab + β-2-microglobulin + MHC antigen + NYESO peptide
    
  • 6gv4 – hFab + parechovirus proteins + RNA - Cryo EM
    
  • 6cw2 – hFab + histone acetyltransferase + transcriptional adapter
    
  • 6c5v – hFab + herpesvirus proteins - Cryo EM
    
  • 6c08 – hFab + amino acid transporter + Arg
    

• Human anti-HIV Fab: protein higher complexes

• • 1g9m, 1g9n, 1gc1, 2i5y, 2i60, 2nxy, 2nxz, 2ny0, 2ny1, 2ny2, 2ny3, 2ny4, 2ny5, 2ny6, 3jwd, 3jwo, 5a8h, 5a7x, 4r4h, 4h8w - hFab anti-HIV + envelope glycoprotein gp120 + CD4
    
  • 5jsa, 5js9, 5c7k, 5v8l, 5v8m - hFab anti-HIV + envelope glycoprotein gp120 + gp41
    
  • 4r4n, 4r4f - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide
    
  • 3lqa, 2qad - hFab anti-HIV + CD4 + gp41
    

• Mouse Fab: protein higher complexes

• • 5w3e, 5w3l, 5w3m, 5w3o, 5w3p - mFab C5 + Rhinovirus protein 1 + protein 2 + protein 3 + protein 4
    
  • 3gb7, 2p7t, 2h8p, 2hfe, 2atk, 4wfh, 4wfg, 4wff, 4wfe, 5vk6, 5vke, 5vkh, 6by2, 6by3 - mFab + KcsA K+ channel + ion
    
  • 3or6, 3or7, 3ogc, 3fb7, 3f7v, 3f7y, 3fb5, 3fb6, 3fb8, 3iga, 2itc, 2itd, 2nlj, 2bob, 2boc, 1s5h, 1r3i, 1r3j, 1r3k, 1r3l, 1k4c, 1k4d, 3hpl - mFab + KcsA K+ channel (mutant) + ion
    
  • 2fd6 – mFab ATN-615 + urokinase-type plasminogen activator + urokinase plasminogen receptor
    
  • 4k24 – mFab + urokinase-type plasminogen activator + urokinase plasminogen receptor + vitronectin
    
  • 1j5o – mFab + reverse transcriptase + DNA
    
  • 1qkz – mFab + protein G prime + major outer membrane protein peptide
    
  • 2ibz – mFab + cytochrome bc1 complex + stigmatellin
    
  • 6jmq, 6jmr – mFab + large neutral amino acid transporter + 4f2 cell-surface antigen
    
  • 6qno - mFab + guanine nucleotide-binding protein + transducin + rhodopsin – Cryo EM
    

• Full Immunoglobulin

• • 1hzh - hFab IgG B12
    
  • 1iga - hIgA1 - model
    

• Fc Fragments

• • 3dnk - hFc Igg1br />
  • 1qp1 – hFc BRE
    
  • 3muh – hFc PG9
    
  • 4bsv, 4bsw – hFc heterodimeric (mutant)
    
  • 1f6a - hFc IgE + high-affinity receptor Fc (ε) RI (α)
    
  • 1fp5 - hFc IgE C ε 3-C ε 4
    

• Fv Fragments

• • 3zhd, 3zhk, 3zhl – hFv scaffold
    
  • 4u3x – hFv + lysozyme
    
  • 3dur, 3dus, 3duu, 3dv4, 3dv6 – mFv + Ig-like protein
    
  • 3hb3 – mFv + cytochrome c oxidase subunit 1-β
    
  • 1qle - mFv + cytochrome c oxidase
    
  • 6oik - mFv + AChR + guanine nucleotide-binding protein + transducin – Cryo EM
    

• Single chain variable fragment (scFv)

• • 6ehy, 6ehv, 6ehw, 6ehx, 5c2b, 5wym, 1x9q, 2a9m, 3kdm, 4buh, 3u6r, 3auv – hscFv
    
  • 4x4x, 4x4y, 2a9n – hscFv (mutant)
    
  • 3juy, 4ut7 – hscFv anti-HIV
    
  • 4h0g, 4nkd, 4nkm, 4nko, 3nn8, 3bd3, 3bd4, 3bd5, 2gjj, 5b3n, 4laq, 4gqp, 3umt – mscFv
    
  • 1p4i – mscFv (mutant)
    
  • 4p49, 4p48, 4ouo, 5vf6 – scFv - chicken
    

• Single chain variable fragment complex

• • 5lbs – hscFv + zika envelope protein E
    
  • 5ljy – hscFv + Hantaan virus envelope protein
    
  • 6pcu – hscFv + rotavirus capsid protein
    
  • 5wn9 – hscFv + respiratory syncytial virus envelope protein
    
  • 4nik – hscFv + gankyrin
    
  • 5jz7 – hscFv + NGF
    
  • 4kv5 – hscFv + TGF
    
  • 2ybr, 2yc1 – hscFv + CN2 toxin
    
  • 5ujz, 5uk0, 5uk1, 5uk2 - hscFv + hemagglutinin – Cryo EM
    
  • 4v1d - hscFv + mammal toxin CN2
    
  • 5dhz, 5dhy, 5dhx, 5dhv – hscFv anti-HIV + HIV REV
    
  • 3ab0 – mscFv + BCLA protein
    
  • 5jyl, 5jym – mscFv + cadherin
    
  • 5f3j – mscFv + duffy receptor
    
  • 5dfw, 6ejg, 6ejm, 6ek2 – mscFv + CD81
    
  • 2kh2 – mscFv + IL-1 - NMR
    
  • 4yqx – mscFv + IL-2
    
  • 3h3b – mscFv + ERBB2
    
  • 5ogi – mscFv + hexon protein
    
  • 3h3b, 6eqc – mscFv + hexon protein – Cryo EM
    
  • 4f9p, 4f9l – mscFv + BTN3A1
    
  • 5aam, 5aaw – mscFv + Dengue virus envelope protein
    
  • 5kov – mscFv + Astrovirus envelope protein
    
  • 1dzb, 2znx – mscFv + lysozyme
    
  • 1a14, 1nmc – mscFv + neuraminidase
    
  • 1fo0, 1kj2, 1nam – mscFv + TCR + MHC + peptide
    
  • 5d9q – hscFv + antibody + gp120 + gp40
    

• Single chain variable fragment complex with small molecule

• • 5i4f, 5vf2 – mscFv + mannobiose
    
  • 4h0i – mscFv + mannopyranoside
    
  • 2cju – mscFv + phOxGABA
    
  • 2uud – mscFv + hapten
    
  • 5j74, 5j75 – hscFv + inhibitor
    
  • 4lar – hscFv + dexedrine
    
  • 4las – hscFv + amphetamine derivative
    

• Single chain variable fragment complex with peptide

• • 5yax – hscFv + HBV peptide
    
  • 5npi, 5npj – mscFv + hepatitis peptide
    
  • 5a2i, 5aij, 5a2k, 5a2l – mscFv + TN peptide
    
  • 1p4b – mscFv + GCN4 peptide
    
  • 4h0h, 5fxc, 5owp, 1ktr – mscFv + peptide
    

• Single domain antibody VHH or Camelid antibody or nanobody NB80

• • 5i0z, 5c6w – hVHH
    
  • 6cnw – hyVHH - hybrid
    
  • 4ppt, 4idl, 1shm, 2xa3, 5sv4, 4w81, 4w70, 4w68, 4tyu, 6ezw, 6f0d, 5nlu, 4krn, 4poy, 1sjv, 1u0q, 3qxu, 3qxw, 4b50, 5tp3, 1sjx, 4qgy, 5h8d, 4b5e, 6fys – LgVHH
    
  • 1g9e – LgVHH - NMR
    
  • 4u05 – LgVHH (mutant)
    
  • 4w2p, 6apo, 6apq – LgVHH anti-marburg virus
    
  • 6ck8 – LgVHH anti-influenza virus
    
  • 3r0m – LgVHH anti-HIV
    
  • 2xxc – ViVHH anti-HIV - vicuna
    
  • 6cwk – ViVHH anti-ricin
    
  • 5u64, 5u65, 1f2x, 1yc7, 5e7b, 5m7q, 5jmr, 3dwt, 3tpk, 3ln9 – cVHH - camel
    
  • 1yc8, 3eak – cVHH (mutant)
    
  • 6itp, 6itq – cVHH anti-cortisol
    
  • 6t2j – syVHH
    

• VHH binary complexes

• • 6oan, 6oao – hVHH + DBP
    
  • 1i3u, 1i3v, 1dq0 - LgVHH + hapten
    
  • 3qxt, 3qxv – LgVHH + methotrexate
    
  • 4pou, 1bzq – LgVHH + RNAse 1
    
  • 4nc1, 4nbx, 4nby, 4nbz, 4nc0, 4nc2 – LgVHH + TcdA
    
  • 3k81, 3stb, 4dk3, 4dk6, 4dka, 3k7u, 3k80 – LgVHH + RNA editing complex protein
    
  • 5tok, 5toj – LgVHH + F glycoprotein
    
  • 5boz, 5j57, 5j56, 5e1h, 5sv3 – LgVHH + ricin
    
  • 5hm1 – LgVHH + gp41
    
  • 5o2u – LgVHH + p24
    
  • 4grw – LgVHH + IL-23
    
  • 5nqw – LgVHH + IGE-FC
    
  • 4hep, 4hem – LgVHH + BPP
    
  • 4w2q, 4w2o, 6app – LgVHH + Marburg virus nucleoprotein
    
  • 6fyt, 6fyu, 6fyw – LgVHH + Influenza virus hemagglutinin
    
  • 6ana, 6and, 6ani – LgVHH + mouse antibody
    
  • 4krl, 4krm – LgVHH + EGFR
    
  • 3rjq – LgVHH anti-HIV + gp120
    
  • 2bse – LgVHH + receptor-binding protein
    
  • 4ej1, 4eiz, 4eig – LgVHH + DHFR
    
  • 3p0g, 4lde, 4ldl, 4ldo – LgVHH + adrenergic receptor
    
  • 4n1h, 4m3k, 5lwf – LgVHH + beta-lactamase
    
  • 5m95, 5m94, 4wgw, 4wgv – LgVHH + metal cation transporter
    
  • 5h8o – LgVHH + ASC
    
  • 3k3q – LgVHH + Botox
    
  • 4wem, 4wen, 4weu – LgVHH + adhesin
    
  • 4p2c – LgVHH + Shiga toxin
    
  • 4aq1 – LgVHH + SBSB
    
  • 6h7j, 6h7l, 6h7m, 6h7n – lgVHH + thioredoxin + adrenergic receptor
    
  • 1jto, 1jtp, 1jtt, 1ri8, 1xfp, 1zmy, 1zv5, 1zvh, 4i0c, 1op9, 1mel, 1rjc, 1zvy – cVHH + lysozyme
    
  • 2x89 – cVHH + β-2-microglobulin
    
  • 1kxq, 1kxt, 1kxv – cVHH + α-amylase
    
  • 3qsk, 2p42, 2p43, 2p44, 2p45, 2p46, 2p47, 2p48, 2p49, 2p4a – cVHH + RNAse 1
    
  • 4tvs – viVHH + LAP1
    
  • 4yga – ViVHH + CDPK1
    
  • 5l21 – ViVHH + Botox
    
  • 2xt1, 2xxm – ViVHH anti-HIV + HIV capsid
    
  • 5o04, 5o02, 5o03, 5o05, 5tjw, 5omn, 4x7c, 4x7d, 4x7e, 4x7f, 5m30 – ViVHH + virus capsid
    
  • 2xv6 – ViVHH + p24
    
  • 5hvf, 5hvg, 5hvh – ViVHH + carboxypeptidase
    
  • 5hgg, 5lhr, 5lhq, 5lhp, 5lhn – ViVHH + urokinase-type plasminogen activator
    
  • 5vxm, 5vxj, 5vxk, 5vxl, 5vlj - ViVHH + invasion IpaD
    
  • 5u4l, 4z9k, 4lhj, 4lgp, 6cwg, 5u4m, 6obc, 6obe, 6obg, 6obm, 6obo, 6oca, 6ocd – ViVHH anti-ricin + ricin
    
  • 6knm - cVHH + apelin receptor
    
  • 6sc5, 6sc6, 6sc7, 6sc8, 6sc9 – syVHH + RNF31
    

• VHH ternary complexes

• • 3v0a – LgVHH + BONT/A1 + NTNH
    
  • 3sn6 – LgVHH + adrenergic receptor + guanine nucleotide-binding protein
    
  • 6oya - LgVHH + guanine nucleotide-binding protein + transducin + rhodopsin + GT-alpha/GI1-alpha – Cryo EM
    
  • 4laj - LgVHH + envelope glycoprotein gp120 + CD4
    
  • 4orz – LgVHH + tyrosine protein kinase HCK + NEF
    
  • 4kro, 4krp – LgVHH + antibody + EGFR
    
  • 5j1s, 5j1t – ViVHH + Torsin + LULL1
    
  • 5uk4, 5ukb – ViVHH + virus capsid + RNA
    
  • 5jmo – cVHH + furin + CMK inhibitor
    
  • 5fuc – cVHH + IL-6 + IL-6 receptor
    
  • 6h7o, 6ibl – cVHH + thioredoxin + adrenergic receptor
    

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