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NudT16

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==Introduction==
==Introduction==
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NudT16 is a hydrolase and belongs to the nucleoside diphosphate-linked moiety X (Nudix) family. This protein regulates levels of 53BP1 which is a protein that recruits other proteins to the site of a DNA breakage. NudT16 has also shown in vitro to remove ADP-ribosylation through its hydrolase activities.
==Structure==
==Structure==

Revision as of 14:52, 29 June 2020

Contents

Introduction

NudT16 is a hydrolase and belongs to the nucleoside diphosphate-linked moiety X (Nudix) family. This protein regulates levels of 53BP1 which is a protein that recruits other proteins to the site of a DNA breakage. NudT16 has also shown in vitro to remove ADP-ribosylation through its hydrolase activities.

Structure

Crystal structure of HsNUDT16 in complex with diADPR (soaked)

Drag the structure with the mouse to rotate
NudT16
NudT16


Function

Disease

Relevance

Structural highlights

</StructureSection>

References

Proteopedia Page Contributors and Editors (what is this?)

Hannah Campbell, Tihitina Y Aytenfisu, Michal Harel, Sandra B. Gabelli

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