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2wo9

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==MMP12 complex with a beta hydroxy carboxylic acid==
==MMP12 complex with a beta hydroxy carboxylic acid==
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<StructureSection load='2wo9' size='340' side='right' caption='[[2wo9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='2wo9' size='340' side='right'caption='[[2wo9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wo9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WO9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WO9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wo9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WO9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WO9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=068:(3S)-5-(4-ACETYLBIPHENYL-4-YL)-3-HYDROXYPENTANOIC+ACID'>068</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=068:(3S)-5-(4-ACETYLBIPHENYL-4-YL)-3-HYDROXYPENTANOIC+ACID'>068</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[1os9|1os9]], [[1utt|1utt]], [[1y93|1y93]], [[1z3j|1z3j]], [[2w0d|2w0d]], [[1os2|1os2]], [[1jk3|1jk3]], [[1ros|1ros]], [[1utz|1utz]], [[1rmz|1rmz]], [[1jiz|1jiz]], [[2woa|2woa]], [[2wo8|2wo8]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[1os9|1os9]], [[1utt|1utt]], [[1y93|1y93]], [[1z3j|1z3j]], [[2w0d|2w0d]], [[1os2|1os2]], [[1jk3|1jk3]], [[1ros|1ros]], [[1utz|1utz]], [[1rmz|1rmz]], [[1jiz|1jiz]], [[2woa|2woa]], [[2wo8|2wo8]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wo9 OCA], [http://pdbe.org/2wo9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wo9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wo9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wo9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wo9 OCA], [http://pdbe.org/2wo9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wo9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wo9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wo9 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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==See Also==
==See Also==
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*[[Matrix metalloproteinase|Matrix metalloproteinase]]
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*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Macrophage elastase]]
[[Category: Macrophage elastase]]
[[Category: Amour, A J]]
[[Category: Amour, A J]]

Revision as of 08:58, 1 July 2020

MMP12 complex with a beta hydroxy carboxylic acid

PDB ID 2wo9

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