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Cyclin-dependent kinase 3D structures
From Proteopedia
(Difference between revisions)
(New page: ==3D structures of cyclin-dependent kinase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *CDK1 **1dks – ...) |
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**[[1pw2]], [[1hck]], [[1hcl]], [[1b38]], [[4ek3]], [[5ano]] – hCDK2 – human<br /> | **[[1pw2]], [[1hck]], [[1hcl]], [[1b38]], [[4ek3]], [[5ano]] – hCDK2 – human<br /> | ||
**[[1b39]] - hCDK2 T160P<br /> | **[[1b39]] - hCDK2 T160P<br /> | ||
| - | **[[3ns9]], [[3le6]], [[2xmy]], [[2xnb]], [[3lfn]], [[3lfq]], [[3lfs]], [[3ig7]], [[3igg]], [[3fz1]], [[3ezr]], [[3ezv]], [[2w1h]], [[2w17]], [[2w05]], [[2w06]], [[2r64]], [[2vta]], [[2vth]], [[2vti]], [[2vtj]], [[2vtl]], [[2vtm]], [[2vtn]], [[2vto]], [[2vtp]], [[2vtq]], [[2vtr]], [[2vts]], [[2vtt]], [[2vu3]], [[2vv9]], [[2r3f]], [[2r3g]], [[2r3h]], [[2r3i]], [[2r3j]], [[2r3k]], [[2r3l]], [[2r3m]], [[2r3n]], [[2r3o]], [[2r3p]], [[2r3q]], [[2r3r]], [[2j9m]], [[2v0d]], [[2duv]], [[2clx]], [[2fvd]], [[2a4l]], [[1w8c]], [[2a0c]], [[2exm]], [[2bpm]], [[2c68]], [[2c69]], [[2c6i]], [[2c6k]], [[2c6l]], [[2c6m]], [[2c6o]], [[2c6t]], [[2btr]], [[2bts]], [[2b52]], [[2b53]], [[2b54]], [[2b55]], [[2bhe]], [[2bhh]], [[1y8y]], [[1y91]], [[1wcc]], [[1w0x]], [[1pye]], [[1vyz]], [[1vyw]], [[1v1k]], [[1urw]], [[1pxm]], [[1pxn]], [[1pxo]], [[1pxp]], [[1r78]], [[1pf8]], [[1pxi]], [[1pxj]], [[1pxk]], [[1pxl]], [[1oiq]], [[1oir]], [[1oit]], [[1p2a]], [[1h00]], [[1h01]], [[1h07]], [[1h08]], [[1h0v]], [[1h0w]], [[1gz8]], [[1ke5]], [[1ke6]], [[1ke7]], [[1ke8]], [[1ke9]], [[1gih]], [[1gii]], [[1gij]], [[1jvp]], [[1g5s]], [[1jsv]], [[1e1v]], [[1e1x]], [[1fvt]], [[1fvv]], [[1di8]], [[1dm2]], [[1ckp]], [[1aq1]], [[3pxf]], [[3pxq]], [[3pxr]], [[3pxy]], [[3pxz]], [[3py0]], [[3py1]], [[3pj8]], [[3s2p]], [[3ql8]], [[3qqf]], [[3qqg]], [[3qqh]], [[3qqj]], [[3qqk]], [[3qql]], [[3qrt]], [[3qru]], [[3qtq]], [[3qtr]], [[3qts]], [[3qtu]], [[3qtw]], [[3qtx]], [[3qtz]], [[3qu0]], [[3qwj]], [[3qwk]], [[3qx2]], [[3qx4]], [[3qxo]], [[3qxp]], [[3qzf]], [[3qzg]], [[3qzh]], [[3qzi]], [[3r1q]], [[3r1s]], [[3r1y]], [[3r28]], [[3r6x]], [[3r71]], [[3r73]], [[3r7e]], [[3r7i]], [[3r7u]], [[3r7v]], [[3r7y]], [[3r83]], [[3r8l]], [[3r8m]], [[3r8p]], [[3r8u]], [[3r8v]], [[3r8z]], [[3r9d]], [[3r9h]], [[3r9n]], [[3r9o]], [[3rah]], [[3rai]], [[3rak]], [[3ral]], [[3rjc]], [[3rk5]], [[3rk7]], [[3rk9]], [[3rkb]], [[3rm6]], [[3rm7]], [[3rmf]], [[3rni]], [[3roy]], [[3rpo]], [[3rpr]], [[3rpv]], [[3rpy]], [[3rzb]], [[3s00]], [[3s0o]], [[3s1h]], [[3sqq]], [[3sw4]], [[3sw7]], [[3ti1]], [[3tiy]], [[3tiz]], [[3uli]], [[3unj]], [[3unk]], [[3wbl]], [[4acm]], [[4bgh]], [[4ek4]], [[4ek5]], [[4ek6]], [[4ek8]], [[4ez3]], [[4ez7]], [[4fkg]], [[4fki]], [[4fkj]], [[4fkl]], [[4fko]], [[4fkp]], [[4fkq]], [[4fkr]], [[4fks]], [[4fkt]], [[4fku]], [[4fkv]], [[4fkw]], [[4gcj]], [[4kd1]], [[4lyn]], [[4nj3]], [[4bzd]], [[4rj3]], [[5osj]], [[5oo0]], [[5mhq]], [[5k4j]], [[5jq8]], [[5jq5]], [[5iey]], [[5iex]], [[5fp6]], [[5fp5]], [[5d1j]], [[5ank]], [[5anj]], [[5ani]], [[5ang]], [[5ane]], [[5and]], [[5a14]], [[4d1z]], [[4d1x]], [[6guk]], [[6guh]] – hCDK2 + inhibitor<br /> | + | **[[3ns9]], [[3le6]], [[2xmy]], [[2xnb]], [[3lfn]], [[3lfq]], [[3lfs]], [[3ig7]], [[3igg]], [[3fz1]], [[3ezr]], [[3ezv]], [[2w1h]], [[2w17]], [[2w05]], [[2w06]], [[2r64]], [[2vta]], [[2vth]], [[2vti]], [[2vtj]], [[2vtl]], [[2vtm]], [[2vtn]], [[2vto]], [[2vtp]], [[2vtq]], [[2vtr]], [[2vts]], [[2vtt]], [[2vu3]], [[2vv9]], [[2r3f]], [[2r3g]], [[2r3h]], [[2r3i]], [[2r3j]], [[2r3k]], [[2r3l]], [[2r3m]], [[2r3n]], [[2r3o]], [[2r3p]], [[2r3q]], [[2r3r]], [[2j9m]], [[2v0d]], [[2duv]], [[2clx]], [[2fvd]], [[2a4l]], [[1w8c]], [[2a0c]], [[2exm]], [[2bpm]], [[2c68]], [[2c69]], [[2c6i]], [[2c6k]], [[2c6l]], [[2c6m]], [[2c6o]], [[2c6t]], [[2btr]], [[2bts]], [[2b52]], [[2b53]], [[2b54]], [[2b55]], [[2bhe]], [[2bhh]], [[1y8y]], [[1y91]], [[1wcc]], [[1w0x]], [[1pye]], [[1vyz]], [[1vyw]], [[1v1k]], [[1urw]], [[1pxm]], [[1pxn]], [[1pxo]], [[1pxp]], [[1r78]], [[1pf8]], [[1pxi]], [[1pxj]], [[1pxk]], [[1pxl]], [[1oiq]], [[1oir]], [[1oit]], [[1p2a]], [[1h00]], [[1h01]], [[1h07]], [[1h08]], [[1h0v]], [[1h0w]], [[1gz8]], [[1ke5]], [[1ke6]], [[1ke7]], [[1ke8]], [[1ke9]], [[1gih]], [[1gii]], [[1gij]], [[1jvp]], [[1g5s]], [[1jsv]], [[1e1v]], [[1e1x]], [[1fvt]], [[1fvv]], [[1di8]], [[1dm2]], [[1ckp]], [[1aq1]], [[3pxf]], [[3pxq]], [[3pxr]], [[3pxy]], [[3pxz]], [[3py0]], [[3py1]], [[3pj8]], [[3s2p]], [[3ql8]], [[3qqf]], [[3qqg]], [[3qqh]], [[3qqj]], [[3qqk]], [[3qql]], [[3qrt]], [[3qru]], [[3qtq]], [[3qtr]], [[3qts]], [[3qtu]], [[3qtw]], [[3qtx]], [[3qtz]], [[3qu0]], [[3qwj]], [[3qwk]], [[3qx2]], [[3qx4]], [[3qxo]], [[3qxp]], [[3qzf]], [[3qzg]], [[3qzh]], [[3qzi]], [[3r1q]], [[3r1s]], [[3r1y]], [[3r28]], [[3r6x]], [[3r71]], [[3r73]], [[3r7e]], [[3r7i]], [[3r7u]], [[3r7v]], [[3r7y]], [[3r83]], [[3r8l]], [[3r8m]], [[3r8p]], [[3r8u]], [[3r8v]], [[3r8z]], [[3r9d]], [[3r9h]], [[3r9n]], [[3r9o]], [[3rah]], [[3rai]], [[3rak]], [[3ral]], [[3rjc]], [[3rk5]], [[3rk7]], [[3rk9]], [[3rkb]], [[3rm6]], [[3rm7]], [[3rmf]], [[3rni]], [[3roy]], [[3rpo]], [[3rpr]], [[3rpv]], [[3rpy]], [[3rzb]], [[3s00]], [[3s0o]], [[3s1h]], [[3sqq]], [[3sw4]], [[3sw7]], [[3ti1]], [[3tiy]], [[3tiz]], [[3uli]], [[3unj]], [[3unk]], [[3wbl]], [[4acm]], [[4bgh]], [[4ek4]], [[4ek5]], [[4ek6]], [[4ek8]], [[4ez3]], [[4ez7]], [[4fkg]], [[4fki]], [[4fkj]], [[4fkl]], [[4fko]], [[4fkp]], [[4fkq]], [[4fkr]], [[4fks]], [[4fkt]], [[4fku]], [[4fkv]], [[4fkw]], [[4gcj]], [[4kd1]], [[4lyn]], [[4nj3]], [[4bzd]], [[4rj3]], [[5osj]], [[5oo0]], [[5mhq]], [[5k4j]], [[5jq8]], [[5jq5]], [[5iey]], [[5iex]], [[5fp6]], [[5fp5]], [[5d1j]], [[5ank]], [[5anj]], [[5ani]], [[5ang]], [[5ane]], [[5and]], [[5a14]], [[4d1z]], [[4d1x]], [[6guk]], [[6guh]], [[6inl]], [[6jgm]] – hCDK2 + inhibitor<br /> |
**[[6q3b]], [[6q3c]], [[6q3f]], [[6q48]], [[6q49]], [[6q4a]], [[6q4b]], [[6q4c]], [[6q4d]], [[6q4e]], [[6q4f]], [[6q4g]], [[6q4h]], [[6q4i]], [[6q4j]], [[6q4k]] – hCDK2 + fraglite<br /> | **[[6q3b]], [[6q3c]], [[6q3f]], [[6q48]], [[6q49]], [[6q4a]], [[6q4b]], [[6q4c]], [[6q4d]], [[6q4e]], [[6q4f]], [[6q4g]], [[6q4h]], [[6q4i]], [[6q4j]], [[6q4k]] – hCDK2 + fraglite<br /> | ||
**[[2ds1]], [[5osm]], [[5oo3]], [[5oo1]] – hCDK2 (mutant) + inhibitor<br /> | **[[2ds1]], [[5osm]], [[5oo3]], [[5oo1]] – hCDK2 (mutant) + inhibitor<br /> | ||
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**[[2jgz]] - hCDK2 T160P + cyclin B1<br /> | **[[2jgz]] - hCDK2 T160P + cyclin B1<br /> | ||
**[[1w98]], [[5l2w]] - hCDK2 + cyclin E1<br /> | **[[1w98]], [[5l2w]] - hCDK2 + cyclin E1<br /> | ||
| - | **[[2wma]], [[2wmb]], [[2x1n]], [[2wev]], [[2wfy]], [[2whb]], [[2v22]], [[2cch]], [[1okv]], [[1okw]], [[1ol1]], [[1ol2]], [[1urc]], [[1h24]], [[1h25]], [[1h26]], [[1h27]], [[1h28]], [[1gy3]], [[3qhr]], [[3qhw]] - hCDK2 + cyclin A2+peptide ligand<br /> | + | **[[2wma]], [[2wmb]], [[2x1n]], [[2wev]], [[2wfy]], [[2whb]], [[2v22]], [[2cch]], [[1okv]], [[1okw]], [[1ol1]], [[1ol2]], [[1urc]], [[1h24]], [[1h25]], [[1h26]], [[1h27]], [[1h28]], [[1gy3]], [[3qhr]], [[3qhw]], [[6p3w]] - hCDK2 + cyclin A2+peptide ligand<br /> |
**[[2wpa]], [[2wxv]], [[2wih]], [[2wip]], [[3f5x]], [[3eoc]], [[3eid]], [[3ej1]], [[2uzb]], [[2uzd]], [[2uze]], [[2uzl]], [[2uzn]], [[2uzo]], [[2uue]], [[2i40]], [[2bkz]], [[2c5n]], [[2c5o]], [[2c5v]], [[2c5x]], [[2c5y]], [[1ykr]], [[2c4g]], [[1p5e]], [[1pkd]], [[1fin]], [[4bcm]], [[4bcn]], [[4bco]], [[4bcp]], [[4bcq]], [[4cfm]], [[4cfn]], [[4cfu]], [[4cfv]], [[4cfw]], [[4cfx]], [[4fx3]], [[6gva]], [[6guf]], [[6gue]], [[6guc]] – hCDK2 + cyclin A2 + inhibitor<br /> | **[[2wpa]], [[2wxv]], [[2wih]], [[2wip]], [[3f5x]], [[3eoc]], [[3eid]], [[3ej1]], [[2uzb]], [[2uzd]], [[2uze]], [[2uzl]], [[2uzn]], [[2uzo]], [[2uue]], [[2i40]], [[2bkz]], [[2c5n]], [[2c5o]], [[2c5v]], [[2c5x]], [[2c5y]], [[1ykr]], [[2c4g]], [[1p5e]], [[1pkd]], [[1fin]], [[4bcm]], [[4bcn]], [[4bco]], [[4bcp]], [[4bcq]], [[4cfm]], [[4cfn]], [[4cfu]], [[4cfv]], [[4cfw]], [[4cfx]], [[4fx3]], [[6gva]], [[6guf]], [[6gue]], [[6guc]] – hCDK2 + cyclin A2 + inhibitor<br /> | ||
**[[6ath]] - hCDK2 T160P+ cyclin A2 + CDK inhibitor 1B<br /> | **[[6ath]] - hCDK2 T160P+ cyclin A2 + CDK inhibitor 1B<br /> | ||
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**[[2w96]], [[2w99]], [[2w9f]], [[2w9z]] – hCDK4 kinase domain + cyclin D1<br /> | **[[2w96]], [[2w99]], [[2w9f]], [[2w9z]] – hCDK4 kinase domain + cyclin D1<br /> | ||
| + | **[[6p8e]], [[6p8f]], [[6p8g]], [[6p8h]] – hCDK4 (mutant) + cyclin D1 + CDK inhibitor 1B<br /> | ||
**[[3g33]] - hCDK4 + cyclin D3<br /> | **[[3g33]] - hCDK4 + cyclin D3<br /> | ||
**[[5fwp]], [[5fwm]], [[5fwl]], [[5fwk]] - hCDK4-P + HSP 90 + CDC37 – cryo-EM<br /> | **[[5fwp]], [[5fwm]], [[5fwl]], [[5fwk]] - hCDK4-P + HSP 90 + CDC37 – cryo-EM<br /> | ||
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**[[1ua2]] – hCDK7<br /> | **[[1ua2]] – hCDK7<br /> | ||
| + | **[[6o9l]] – hCDK7 in transcription preinitiation complex – Cryo EM<br /> | ||
*CDK8 | *CDK8 | ||
**[[4g6l]], [[4crl]] – hCDK8 + cyclin C <br /> | **[[4g6l]], [[4crl]] – hCDK8 + cyclin C <br /> | ||
| - | **[[3rgf]], [[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4c4l]], [[5bnj]], [[5cei]], [[5fgk]], [[5hbe]], [[5hbh]], [[5hbj]], [[5hnb]], [[5hvy]], [[5i5z]], [[5icp]], [[5idn]], [[5idp]], [[5xs2]], [[5xqx]], [[4f7s]] – hCDK8 + cyclin C + inhibitor<br /> | + | **[[3rgf]], [[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4c4l]], [[5bnj]], [[5cei]], [[5fgk]], [[5hbe]], [[5hbh]], [[5hbj]], [[5hnb]], [[5hvy]], [[5i5z]], [[5icp]], [[5idn]], [[5idp]], [[5xs2]], [[5xqx]], [[4f7s]], [[6qtg]], [[6qtj]], [[6r3s]], [[6t41]] – hCDK8 + cyclin C + inhibitor<br /> |
*CDK9 | *CDK9 | ||
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**[[4cxa]] – hCDK12-P + cyclin K + AMPPNP<br /> | **[[4cxa]] – hCDK12-P + cyclin K + AMPPNP<br /> | ||
**[[6b3e]], [[5acb]], [[6ckx]] – hCDK12-P + cyclin K + inhibitor<br /> | **[[6b3e]], [[5acb]], [[6ckx]] – hCDK12-P + cyclin K + inhibitor<br /> | ||
| + | **[[6td3]] - hCDK12-P + cyclin K + DDB1<br /> | ||
*CDK13 | *CDK13 | ||
Revision as of 07:02, 9 July 2020
3D structures of cyclin-dependent kinase
Updated on 09-July-2020
