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2zca

From Proteopedia

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[[Image:2zca.png|left|200px]]
 
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{{STRUCTURE_2zca| PDB=2zca | SCENE= }}
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==Crystal Structure of TTHB189, a CRISPR-associated protein, Cse2 family from Thermus thermophilus HB8==
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<StructureSection load='2zca' size='340' side='right'caption='[[2zca]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===Crystal Structure of TTHB189, a CRISPR-associated protein, Cse2 family from Thermus thermophilus HB8===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2zca]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZCA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZCA FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zca OCA], [http://pdbe.org/2zca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zca RCSB], [http://www.ebi.ac.uk/pdbsum/2zca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zca ProSAT], [http://www.topsan.org/Proteins/RSGI/2zca TOPSAN]</span></td></tr>
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[[2zca]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZCA OCA].
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</table>
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== Function ==
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==Reference==
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[[http://www.uniprot.org/uniprot/CSE2_THET8 CSE2_THET8]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
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<ref group="xtra">PMID:018798563</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Thermus thermophilus]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Agari, Y.]]
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Check<jmol>
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[[Category: Kuramitsu, S.]]
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<jmolCheckbox>
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/2zca_consurf.spt"</scriptWhenChecked>
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[[Category: Shinkai, A.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Yokoyama, S.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zca ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
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[[Category: Large Structures]]
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[[Category: Agari, Y]]
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[[Category: Kuramitsu, S]]
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[[Category: Structural genomic]]
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[[Category: Shinkai, A]]
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[[Category: Yokoyama, S]]
[[Category: Crispr]]
[[Category: Crispr]]
[[Category: Cse2]]
[[Category: Cse2]]
[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Plasmid]]
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Unknown function]]
[[Category: Unknown function]]

Current revision

Crystal Structure of TTHB189, a CRISPR-associated protein, Cse2 family from Thermus thermophilus HB8

PDB ID 2zca

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