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7cgr
From Proteopedia
(Difference between revisions)
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==Crystal structure of Azospirillum brasilense L-arabinose 1-dehydrogenase E147A mutant (NADP and glycerol bound form)== | ==Crystal structure of Azospirillum brasilense L-arabinose 1-dehydrogenase E147A mutant (NADP and glycerol bound form)== | ||
| - | <StructureSection load='7cgr' size='340' side='right'caption='[[7cgr]]' scene=''> | + | <StructureSection load='7cgr' size='340' side='right'caption='[[7cgr]], [[Resolution|resolution]] 2.09Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CGR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CGR FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7cgr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29145 Atcc 29145]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CGR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CGR FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cgr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cgr OCA], [http://pdbe.org/7cgr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cgr RCSB], [http://www.ebi.ac.uk/pdbsum/7cgr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cgr ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">araA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192 ATCC 29145])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cgr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cgr OCA], [http://pdbe.org/7cgr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cgr RCSB], [http://www.ebi.ac.uk/pdbsum/7cgr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cgr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ARAA_AZOBR ARAA_AZOBR]] Catalyzes the NAD(P)(+)-dependent conversion of L-arabinose to L-arabino-gamma-lactone. Is involved in a degradation pathway of L-arabinose that allows A.brasilense to grow on L-arabinose as a sole carbon source. Prefers NADP(+) to NAD(+) as electron acceptor. Displays high catalytic efficiency for both L-arabinose and D-galactose in vitro. However, the enzyme appears to be involved in the metabolism of L-arabinose but not D-galactose in vivo. To a lesser extent, is also active on D-talose and D-xylose as substrates in vitro, but not with D-arabinose, D-glucose, D-ribose, L-xylose, L-mannose, L-lyxose, and D-fructose.<ref>PMID:16326697</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Atcc 29145]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Watanabe S]] | + | [[Category: Watanabe, S]] |
| - | [[Category: Watanabe Y]] | + | [[Category: Watanabe, Y]] |
| - | [[Category: Yoshiwara K]] | + | [[Category: Yoshiwara, K]] |
| + | [[Category: Gfo/idh/moca protein family]] | ||
| + | [[Category: L-arabinose metabolism]] | ||
| + | [[Category: Nadp-dependent dehydrogenase]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 10:11, 12 August 2020
Crystal structure of Azospirillum brasilense L-arabinose 1-dehydrogenase E147A mutant (NADP and glycerol bound form)
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