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5ndx
From Proteopedia
(Difference between revisions)
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==The bacterial orthologue of Human a-L-iduronidase does not need N-glycan post-translational modifications to be catalytically competent: Crystallography and QM/MM insights into Mucopolysaccharidosis I== | ==The bacterial orthologue of Human a-L-iduronidase does not need N-glycan post-translational modifications to be catalytically competent: Crystallography and QM/MM insights into Mucopolysaccharidosis I== | ||
| - | <StructureSection load='5ndx' size='340' side='right' caption='[[5ndx]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='5ndx' size='340' side='right'caption='[[5ndx]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ndx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDX OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5ndx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NDX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NDX FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8U8:(2~{R},3~{S},4~{S},5~{R},6~{S})-6-(4-methyl-2-oxidanylidene-chromen-7-yl)oxy-3,4,5-tris(oxidanyl)oxane-2-carboxylic+acid'>8U8</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8U8:(2~{R},3~{S},4~{S},5~{R},6~{S})-6-(4-methyl-2-oxidanylidene-chromen-7-yl)oxy-3,4,5-tris(oxidanyl)oxane-2-carboxylic+acid'>8U8</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ndx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ndx OCA], [http://pdbe.org/5ndx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ndx RCSB], [http://www.ebi.ac.uk/pdbsum/5ndx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ndx ProSAT]</span></td></tr> |
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Castro-Lopez, J]] | [[Category: Castro-Lopez, J]] | ||
[[Category: Hurtado-Guerrero, R]] | [[Category: Hurtado-Guerrero, R]] | ||
Revision as of 12:02, 26 August 2020
The bacterial orthologue of Human a-L-iduronidase does not need N-glycan post-translational modifications to be catalytically competent: Crystallography and QM/MM insights into Mucopolysaccharidosis I
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Categories: Large Structures | Castro-Lopez, J | Hurtado-Guerrero, R | Jimenez-Garcia, M J | Millan, C | Nieto, P | Raich, L | Rovira, C | Uson, I | Valero-Gonzalez, J | Catalytic itinerary | Catalytic mechanism | Human a-l-iduronidase | Hydrolase | Iduronidase | Mucopolysaccharidosis i | N-glycosylation site | Reaction coordinate | Rhizobium leguminosarum
