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5sga

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[[Image:5sga.gif|left|200px]]<br /><applet load="5sga" size="350" color="white" frame="true" align="right" caption="5sga, resolution 1.8&Aring;" />
 
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'''STRUCTURES OF PRODUCT AND INHIBITOR COMPLEXES OF STREPTOMYCES GRISEUS PROTEASE A AT 1.8 ANGSTROMS RESOLUTION. A MODEL FOR SERINE PROTEASE CATALYSIS'''<br />
 
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==About this Structure==
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==Structures of product and inhibitor complexes of Streptomyces griseus protease a at 1.8 Angstroms resolution. a model for serine protease catalysis==
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5SGA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus] with <scene name='pdbligand=ACE:'>ACE</scene> as [[ligand]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SGA OCA].
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<StructureSection load='5sga' size='340' side='right'caption='[[5sga]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5sga]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_griseus"_krainsky_1914 "actinomyces griseus" krainsky 1914]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SGA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5SGA FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5sga FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sga OCA], [http://pdbe.org/5sga PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5sga RCSB], [http://www.ebi.ac.uk/pdbsum/5sga PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5sga ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PRTA_STRGR PRTA_STRGR]] Has a primary specificity for large aliphatic or aromatic amino acids.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sg/5sga_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=5sga ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis., James MN, Sielecki AR, Brayer GD, Delbaere LT, Bauer CA, J Mol Biol. 1980 Nov 25;144(1):43-88. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6783761 6783761]
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*[[Proteinase|Proteinase]]
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[[Category: Single protein]]
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*[[Proteinase 3D structures|Proteinase 3D structures]]
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[[Category: Streptomyces griseus]]
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__TOC__
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[[Category: James, M N.G.]]
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</StructureSection>
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[[Category: Sielecki, A R.]]
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[[Category: Actinomyces griseus krainsky 1914]]
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[[Category: ACE]]
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[[Category: Large Structures]]
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[[Category: hydrolase (serine proteinase)]]
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[[Category: James, M N.G]]
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[[Category: Sielecki, A R]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Mar 18 20:00:06 2008''
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine proteinase]]

Current revision

Structures of product and inhibitor complexes of Streptomyces griseus protease a at 1.8 Angstroms resolution. a model for serine protease catalysis

PDB ID 5sga

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