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3i3h

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[[Image:3i3h.png|left|200px]]
 
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==Crystal structure of Bothropstoxin-I crystallized at 291K==
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The line below this paragraph, containing "STRUCTURE_3i3h", creates the "Structure Box" on the page.
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<StructureSection load='3i3h' size='340' side='right'caption='[[3i3h]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3i3h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I3H OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3I3H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qog|2qog]], [[2oqd|2oqd]], [[2ok9|2ok9]], [[3i3i|3i3i]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3i3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i3h OCA], [http://pdbe.org/3i3h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i3h RCSB], [http://www.ebi.ac.uk/pdbsum/3i3h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i3h ProSAT]</span></td></tr>
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{{STRUCTURE_3i3h| PDB=3i3h | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of Bothropstoxin-I crystallized at 291K===
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[[http://www.uniprot.org/uniprot/PA2B1_BOTJR PA2B1_BOTJR]] Snake venom phospholipase A2 homolog that lacks enzymatic activity. In vivo, induces muscle necrosis, accompanied by polymorphonuclear cell infiltration, and edema in the mouse paw. Damages artificial and myoblast membranes by a calcium-independent mechanism. Has bactericidal activity.<ref>PMID:3176051</ref> <ref>PMID:11018293</ref> <ref>PMID:11829743</ref> <ref>PMID:12079495</ref> <ref>PMID:17346668</ref> <ref>PMID:18160090</ref> <ref>PMID:17157889</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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[[3i3h]] is a 2 chain structure of [[Phospholipase A2]] with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I3H OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/3i3h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i3h ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phospholipase A2]]
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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*[[Phospholipase A2 homolog|Phospholipase A2 homolog]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bothrops jararacussu]]
[[Category: Bothrops jararacussu]]
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[[Category: Fontes, M R.M.]]
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[[Category: Large Structures]]
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[[Category: Marchi-Salvador, D P.]]
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[[Category: Fontes, M R.M]]
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[[Category: Salvador, G H.M.]]
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[[Category: Marchi-Salvador, D P]]
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[[Category: Soares, A M.]]
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[[Category: Salvador, G H.M]]
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[[Category: Soares, A M]]
[[Category: Antimicrobial]]
[[Category: Antimicrobial]]
[[Category: Bothropstoxin-i]]
[[Category: Bothropstoxin-i]]

Current revision

Crystal structure of Bothropstoxin-I crystallized at 291K

PDB ID 3i3h

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