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2pwa
From Proteopedia
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| - | [[Image:2pwa.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution== | |
| - | + | <StructureSection load='2pwa' size='340' side='right'caption='[[2pwa]], [[Resolution|resolution]] 0.83Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | | | + | <table><tr><td colspan='2'>[[2pwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2PWA FirstGlance]. <br> |
| - | | | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B2A:ALANINE+BORONIC+ACID'>B2A</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ic6|1ic6]], [[2pwb|2pwb]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2pwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwa OCA], [http://pdbe.org/2pwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pwa RCSB], [http://www.ebi.ac.uk/pdbsum/2pwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwa ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| + | [[http://www.uniprot.org/uniprot/PRTK_TRIAL PRTK_TRIAL]] Hydrolyzes keratin at aromatic and hydrophobic residues. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwa_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwa ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Proteinase|Proteinase]] | |
| - | + | *[[Proteinase 3D structures|Proteinase 3D structures]] | |
| - | == | + | __TOC__ |
| - | + | </StructureSection> | |
[[Category: Engyodontium album]] | [[Category: Engyodontium album]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Peptidase K]] | [[Category: Peptidase K]] | ||
| - | + | [[Category: Betzel, C]] | |
| - | [[Category: Betzel, C | + | [[Category: Jain, R]] |
| - | [[Category: Jain, R | + | [[Category: Kaur, P]] |
| - | [[Category: Kaur, P | + | [[Category: Perbandt, M]] |
| - | [[Category: Perbandt, M | + | [[Category: Sharma, S]] |
| - | [[Category: Sharma, S | + | [[Category: Singh, N]] |
| - | [[Category: Singh, N | + | [[Category: Singh, T P]] |
| - | [[Category: Singh, T P | + | [[Category: Srinivasan, A]] |
| - | [[Category: Srinivasan, A | + | [[Category: Alanine boronic acid]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| - | [[Category: | + | [[Category: Proteinase k]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution
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