Moesin

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(New page: <StructureSection load='1sgh' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Moesin''' ('''M'''embrane-'''O'''rganizing '''E'''xtension '''S'''...)
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<StructureSection load='4yl8' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='1sgh' size='340' side='right' caption='Caption for this structure' scene=''>
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== Function ==
== Function ==
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[[1sgh]] - hMO FERM domain + EBP50 peptide <br />
[[1sgh]] - hMO FERM domain + EBP50 peptide <br />
[[2i1k]], [[2i1j]] - MO - armyworm <br />
[[2i1k]], [[2i1j]] - MO - armyworm <br />
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[[4yl8]] - MO + Crumbs - ''Drosophila melanogaster'' <br />
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[[4yl8]] - MO + Crumbs - mouse <br />
== References ==
== References ==
<references/>
<references/>

Revision as of 08:20, 15 October 2020

Caption for this structure

Drag the structure with the mouse to rotate

3D structures of moesin

3u8z - hMO FERM domain 1-296 - human
1ef1 - hMO FERM domain + C-terminal domain 487-576
1e5w - hMO FERM domain + 1st helix 297-345
6txq - hMO FERM+helical linker domains - Cryo EM
6txs - hMO FERM+helical linker domains + CD44 peptide
1sgh - hMO FERM domain + EBP50 peptide
2i1k, 2i1j - MO - armyworm
4yl8 - MO + Crumbs - mouse

References

  1. Ansa-Addo EA, Zhang Y, Yang Y, Hussey GS, Howley BV, Salem M, Riesenberg B, Sun S, Rockey DC, Karvar S, Howe PH, Liu B, Li Z. Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-beta signaling. J Clin Invest. 2017 Apr 3;127(4):1321-1337. doi: 10.1172/JCI89281. Epub 2017 Mar , 13. PMID:28287407 doi:http://dx.doi.org/10.1172/JCI89281
  2. Freymuth PS, Fitzsimons HL. The ERM protein Moesin is essential for neuronal morphogenesis and long-term memory in Drosophila. Mol Brain. 2017 Aug 29;10(1):41. doi: 10.1186/s13041-017-0322-y. PMID:28851405 doi:http://dx.doi.org/10.1186/s13041-017-0322-y
  3. Karvar S, Ansa-Addo EA, Suda J, Singh S, Zhu L, Li Z, Rockey DC. Moesin, an Ezrin/Radixin/Moesin Family Member, Regulates Hepatic Fibrosis. Hepatology. 2019 Dec 20. doi: 10.1002/hep.31078. PMID:31860744 doi:http://dx.doi.org/10.1002/hep.31078

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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