This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Signal recognition particle protein

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 9: Line 9:
*Signal recognition particle
*Signal recognition particle
-
**[[1qb2]] – hSRP54 - human<br />
+
**[[6y2z]], [[6y31]] – hSRP54 NG domain 1-296 - human<br />
 +
**[[6y30]] – hSRP54 NG domain (mutant)<br />
 +
**[[1qb2]] – hSRP54 M domain 326-434<br />
**[[4p3f]] – hSRP68 (mutant)<br />
**[[4p3f]] – hSRP68 (mutant)<br />
**[[5m72]], [[5wrv]] – hSRP68 + SRP72<br />
**[[5m72]], [[5wrv]] – hSRP68 + SRP72<br />
Line 24: Line 26:
**[[2ng1]] - TaSRP54-like NG domain (mutant)<br />
**[[2ng1]] - TaSRP54-like NG domain (mutant)<br />
**[[2ffh]] - TaSRP54-like residues 1-425 (mutant)<br />
**[[2ffh]] - TaSRP54-like residues 1-425 (mutant)<br />
-
**[[1kvn]], [[1kvv]] – SRP19 (mutant) – ''Archaeoglobus fulgidus'' – NMR<BR />
+
**[[1kvn]], [[1kvv]] – AfSRP19 (mutant) – ''Archaeoglobus fulgidus'' – NMR<BR />
 +
**[[2jqe]] – AfSRP54 M domain 313-433 – NMR<BR />
**[[3dlu]], [[3dlv]], [[3dm5]] – SRP19 – ''Pyrococcus furiosus''<br />
**[[3dlu]], [[3dlv]], [[3dm5]] – SRP19 – ''Pyrococcus furiosus''<br />
**[[1j8m]] – AaSPR GTPase domain – ''Acicianus ambivalens''<br />
**[[1j8m]] – AaSPR GTPase domain – ''Acicianus ambivalens''<br />
Line 55: Line 58:
**[[2pxb]], [[2pxd]], [[2pxe]], [[2pxf]], [[2pxk]], [[2pxl]], [[2pxq]], [[2pxq]], [[2pxt]], [[2pxu]], [[2pxv]] - EcSRP54-like C terminal + 4.5SRNA domain IV (mutant)<br />
**[[2pxb]], [[2pxd]], [[2pxe]], [[2pxf]], [[2pxk]], [[2pxl]], [[2pxq]], [[2pxq]], [[2pxt]], [[2pxu]], [[2pxv]] - EcSRP54-like C terminal + 4.5SRNA domain IV (mutant)<br />
**[[2j28]] – EcSRP54-like + 70S ribosome – Cryo EM<BR />
**[[2j28]] – EcSRP54-like + 70S ribosome – Cryo EM<BR />
-
**[[4ue4]] – SRP M domain + FTSQ signal sequence + RNA - ''Bacillus subtilis''<br />
+
**[[4ue4]] – SRP M domain + FtsQ signal sequence + RNA - ''Bacillus subtilis''<br />
*Other signal recognition particle complexes
*Other signal recognition particle complexes
-
**[[5l3q]] – hSRP54 + SRP receptor subunit α<br />
+
**[[5l3q]], [[6y32]] – hSRP54 + SRP receptor subunit α<br />
**[[3dep]] - AtSRP43 residues 85-267 + polypeptide<br />
**[[3dep]] - AtSRP43 residues 85-267 + polypeptide<br />
**[[5e4w]] - AtSRP43 chromodomain 2-3 + thioredoxin + ALB3 tail<br />
**[[5e4w]] - AtSRP43 chromodomain 2-3 + thioredoxin + ALB3 tail<br />
Line 65: Line 68:
**[[1jpj]], [[1jpn]], [[2c04]] – TaSRP54-like NG domain + GMPPNP<BR />
**[[1jpj]], [[1jpn]], [[2c04]] – TaSRP54-like NG domain + GMPPNP<BR />
**[[1o87]], [[2c03]] - TaSRP54-like NG domain + GDP<br />
**[[1o87]], [[2c03]] - TaSRP54-like NG domain + GDP<br />
-
**[[1okk]], [[1rj9]], [[2cnw]] - TaSRP54-like NG domain + cell division protein FTSY<br />
+
**[[1okk]], [[1rj9]], [[2cnw]] - TaSRP54-like NG domain + cell division protein FtsY<br />
-
**[[2j7p]] - TaSRP54-like NG domain + cell division protein FTSY + GMPPNP<BR />
+
**[[2j7p]] - TaSRP54-like NG domain + cell division protein FtsY + GMPPNP<BR />
-
**[[5l3s]] - SsSRP54 + cell division protein FTSY<br />
+
**[[5l3s]] - SsSRP54 + cell division protein FtsY<br />
**[[3kl4]] – SsSRP54 residues 2-432 + polypeptide<br />
**[[3kl4]] – SsSRP54 residues 2-432 + polypeptide<br />
**[[5l3v]] - SsSRP54 + GDP<br />
**[[5l3v]] - SsSRP54 + GDP<br />
-
**[[4c7o]] – EcSRP + FTSY + SRP RNA<br />
+
**[[4c7o]] – EcSRP + FtsY + SRP RNA<br />
}}
}}

Revision as of 11:06, 9 November 2020

Human SRP9 (grey and pink) +SRP14 (green and yellow) complex with 7S RNA, GDP and sulfate 1e8o

Drag the structure with the mouse to rotate

3D structures of signal recognition particle

Updated on 09-November-2020

References

  1. Halic M, Beckmann R. The signal recognition particle and its interactions during protein targeting. Curr Opin Struct Biol. 2005 Feb;15(1):116-25. PMID:15718142 doi:http://dx.doi.org/10.1016/j.sbi.2005.01.013
  2. Bovia F, Fornallaz M, Leffers H, Strub K. The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs. Mol Biol Cell. 1995 Apr;6(4):471-84. PMID:7542942
  3. Dean KA, von Ahsen O, Gorlich D, Fried HM. Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin. J Cell Sci. 2001 Oct;114(Pt 19):3479-85. PMID:11682607
  4. Gowda K, Black SD, Moeller I, Sakakibara Y, Liu MC, Zwieb C. Protein SRP54 of human signal recognition particle: cloning, expression, and comparative analysis of functional sites. Gene. 1998 Jan 30;207(2):197-207. PMID:9511762
  5. Lutcke H, Prehn S, Ashford AJ, Remus M, Frank R, Dobberstein B. Assembly of the 68- and 72-kD proteins of signal recognition particle with 7S RNA. J Cell Biol. 1993 Jun;121(5):977-85. PMID:8388879

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Personal tools