1d4y

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[[Image:1d4y.gif|left|200px]]
[[Image:1d4y.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1d4y |SIZE=350|CAPTION= <scene name='initialview01'>1d4y</scene>, resolution 1.97&Aring;
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The line below this paragraph, containing "STRUCTURE_1d4y", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=TPV:N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE'>TPV</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1d4y| PDB=1d4y | SCENE= }}
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|RELATEDENTRY=[[1d4s|1D4S]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d4y OCA], [http://www.ebi.ac.uk/pdbsum/1d4y PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1d4y RCSB]</span>
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}}
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'''HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX'''
'''HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX'''
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[[Category: Janakiraman, M N.]]
[[Category: Janakiraman, M N.]]
[[Category: Watenpaugh, K D.]]
[[Category: Watenpaugh, K D.]]
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[[Category: acid protease]]
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[[Category: Acid protease]]
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[[Category: aspartyl protease]]
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[[Category: Aspartyl protease]]
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[[Category: hydrolase]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:27:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:34:51 2008''
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Revision as of 10:27, 2 May 2008

Template:STRUCTURE 1d4y

HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX


About this Structure

1D4Y is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors., Thaisrivongs S, Skulnick HI, Turner SR, Strohbach JW, Tommasi RA, Johnson PD, Aristoff PA, Judge TM, Gammill RB, Morris JK, Romines KR, Chrusciel RA, Hinshaw RR, Chong KT, Tarpley WG, Poppe SM, Slade DE, Lynn JC, Horng MM, Tomich PK, Seest EP, Dolak LA, Howe WJ, Howard GM, Watenpaugh KD, et al., J Med Chem. 1996 Oct 25;39(22):4349-53. PMID:8893827 Page seeded by OCA on Fri May 2 13:27:29 2008

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