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5wts

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==Green fluorescent protein linked peptide inhibitor PMI in complex with mdm2==
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==Green fluorescent protein linked MTide-02 inhibitor in complex with mdm2==
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<StructureSection load='5wts' size='340' side='right' caption='[[5wts]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='5wts' size='340' side='right'caption='[[5wts]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wts]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeqvi Aeqvi] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WTS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WTS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wts]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeqvi Aeqvi] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WTS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5WTS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRO:{2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CRO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CRO:{2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CRO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6100 AEQVI]), MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wts OCA], [http://pdbe.org/5wts PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wts RCSB], [http://www.ebi.ac.uk/pdbsum/5wts PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wts ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RING-type_E3_ubiquitin_transferase RING-type E3 ubiquitin transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.27 2.3.2.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5wts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wts OCA], [http://pdbe.org/5wts PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wts RCSB], [http://www.ebi.ac.uk/pdbsum/5wts PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wts ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
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*[[MDM2|MDM2]]
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*[[MDM2 3D structures|MDM2 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Aeqvi]]
[[Category: Aeqvi]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: RING-type E3 ubiquitin transferase]]
[[Category: Ghadessy, F J]]
[[Category: Ghadessy, F J]]
[[Category: Robinson, R C]]
[[Category: Robinson, R C]]
[[Category: Wongsantichon, J]]
[[Category: Wongsantichon, J]]
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[[Category: Complex]]
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[[Category: Fluorescent protein-inhibitor complex]]
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[[Category: Ligase-ligase inhibitor complex]]
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Current revision

Green fluorescent protein linked MTide-02 inhibitor in complex with mdm2

PDB ID 5wts

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