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6vzd
From Proteopedia
(Difference between revisions)
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==N-terminal domain of mouse surfactant protein B (K46E/R51E mutant) with bound lipid== | ==N-terminal domain of mouse surfactant protein B (K46E/R51E mutant) with bound lipid== | ||
| - | <StructureSection load='6vzd' size='340' side='right'caption='[[6vzd]]' scene=''> | + | <StructureSection load='6vzd' size='340' side='right'caption='[[6vzd]], [[Resolution|resolution]] 1.88Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VZD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6VZD FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6vzd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VZD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6VZD FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6vzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vzd OCA], [http://pdbe.org/6vzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vzd RCSB], [http://www.ebi.ac.uk/pdbsum/6vzd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vzd ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RXY:(7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl+(9Z)-octadec-9-enoate'>RXY</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sftpb, Sftp3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6vzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vzd OCA], [http://pdbe.org/6vzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vzd RCSB], [http://www.ebi.ac.uk/pdbsum/6vzd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vzd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PSPB_MOUSE PSPB_MOUSE]] Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bodnar | + | [[Category: Lk3 transgenic mice]] |
| - | [[Category: Rapoport | + | [[Category: Bodnar, N O]] |
| + | [[Category: Rapoport, T A]] | ||
| + | [[Category: Lipid transfer]] | ||
| + | [[Category: Lipid-binding]] | ||
| + | [[Category: Saposin-like]] | ||
| + | [[Category: Surfactant protein]] | ||
Revision as of 08:12, 2 December 2020
N-terminal domain of mouse surfactant protein B (K46E/R51E mutant) with bound lipid
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