This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1t4e

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor==
==Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor==
-
<StructureSection load='1t4e' size='340' side='right' caption='[[1t4e]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+
<StructureSection load='1t4e' size='340' side='right'caption='[[1t4e]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1t4e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T4E FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1t4e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4E OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1T4E FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIZ:(4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC+ACID'>DIZ</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIZ:(4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC+ACID'>DIZ</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rv1|1rv1]], [[1ycr|1ycr]], [[1t4f|1t4f]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rv1|1rv1]], [[1ycr|1ycr]], [[1t4f|1t4f]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t4e OCA], [http://pdbe.org/1t4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1t4e RCSB], [http://www.ebi.ac.uk/pdbsum/1t4e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1t4e ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1t4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t4e OCA], [http://pdbe.org/1t4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1t4e RCSB], [http://www.ebi.ac.uk/pdbsum/1t4e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1t4e ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
Line 32: Line 32:
</div>
</div>
<div class="pdbe-citations 1t4e" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1t4e" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[MDM2 3D structures|MDM2 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 37: Line 40:
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Carver, T E]]
[[Category: Carver, T E]]
[[Category: Franks, C F]]
[[Category: Franks, C F]]

Revision as of 11:42, 24 December 2020

Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor

PDB ID 1t4e

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1t4e"
Personal tools