Tyrosine kinase 3D structures
From Proteopedia
(Difference between revisions)
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**[[1jeg]] – mTK + protein-tyrosine phosphatase peptide <br /> | **[[1jeg]] – mTK + protein-tyrosine phosphatase peptide <br /> | ||
**[[1srl]], [[1srm]] - cTK – NMR<br /> | **[[1srl]], [[1srm]] - cTK – NMR<br /> | ||
| - | **[[3fj5]], [[4jz3]], [[4jz4]] - cTK<br /> | + | **[[3fj5]], [[4jz3]], [[4jz4]], [[6xvo]], [[6xvn]] - cTK<br /> |
**[[4le9]], [[4oml]], [[4omm]], [[4omn]], [[4omo]], [[4omp]], [[4omq]], [[5i11]], [[4rtu]], [[4rtx]] - cTK (mutant) <br /> | **[[4le9]], [[4oml]], [[4omm]], [[4omn]], [[4omo]], [[4omp]], [[4omq]], [[5i11]], [[4rtu]], [[4rtx]] - cTK (mutant) <br /> | ||
| + | **[[6xx3]], [[6xx2]], [[6xx5]], [[6xx4]], [[6xx5]], [[6xx2]] - cTK (mutant) + ion<br /> | ||
**[[4hxj]], [[1prl]], [[4qt7]], [[4rty]], [[4rtz]] - cTK + peptide<br /> | **[[4hxj]], [[1prl]], [[4qt7]], [[4rty]], [[4rtz]] - cTK + peptide<br /> | ||
**[[1prm]], [[1rlp]], [[1rlq]], [[1nlo]], [[1nlp]] - cTK + peptide - NMR<br /> | **[[1prm]], [[1rlp]], [[1rlq]], [[1nlo]], [[1nlp]] - cTK + peptide - NMR<br /> | ||
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**[[3mpm]] - hTK Lck kinase domain (mutant) + inhibitor<br /> | **[[3mpm]] - hTK Lck kinase domain (mutant) + inhibitor<br /> | ||
**[[4c3f]] - hTK Lck kinase domain (mutant) + chemotype<br /> | **[[4c3f]] - hTK Lck kinase domain (mutant) + chemotype<br /> | ||
| - | **[[2pl0]] - hTK Lck kinase domain + | + | **[[2pl0]] - hTK Lck kinase domain + anti-cancer drug<br /> |
**[[3kxz]] - hTK Lck kinase domain + probe molecule<br /> | **[[3kxz]] - hTK Lck kinase domain + probe molecule<br /> | ||
**[[1q68]] - hTK Lck residues 6-34 (mutant) + CD4 peptide – NMR<br /> | **[[1q68]] - hTK Lck residues 6-34 (mutant) + CD4 peptide – NMR<br /> | ||
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**[[5f20]], [[5f1z]], [[6ova]] - hTK Tyk2 kinase domain + inhibitor<br /> | **[[5f20]], [[5f1z]], [[6ova]] - hTK Tyk2 kinase domain + inhibitor<br /> | ||
**[[3lxn]], [[3lxp]], [[3nyx]], [[3nz0]], [[4e1z]], [[4e20]], [[4gfo]], [[4gih]], [[4gii]], [[4gj2]], [[4gj3]], [[4py1]], [[5wal]], [[5wev]], [[6dbk]], [[6dbm]] - hTK Tyk2 kinase domain (mutant) + inhibitor<br /> | **[[3lxn]], [[3lxp]], [[3nyx]], [[3nz0]], [[4e1z]], [[4e20]], [[4gfo]], [[4gih]], [[4gii]], [[4gj2]], [[4gj3]], [[4py1]], [[5wal]], [[5wev]], [[6dbk]], [[6dbm]] - hTK Tyk2 kinase domain (mutant) + inhibitor<br /> | ||
| - | **[[6aam]] - hTK Tyk2 kinase domain (mutant) + drug<br /> | + | **[[6aam]], [[6x8g]], [[6x8f]] - hTK Tyk2 kinase domain (mutant) + drug<br /> |
**[[4gvj]] - hTK Tyk2 kinase domain (mutant) + ADP<br /> | **[[4gvj]] - hTK Tyk2 kinase domain (mutant) + ADP<br /> | ||
**[[4oli]] - hTK Tyk2 pseudokinase + kinase domains <br /> | **[[4oli]] - hTK Tyk2 pseudokinase + kinase domains <br /> | ||
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**[[1b55]] - hTK Btk PH domain + inositol-tetrakisphosphate<br /> | **[[1b55]] - hTK Btk PH domain + inositol-tetrakisphosphate<br /> | ||
**[[1bwn]] - hTK Btk PH domain (mutant) + inositol-tetrakisphosphate<br /> | **[[1bwn]] - hTK Btk PH domain (mutant) + inositol-tetrakisphosphate<br /> | ||
| - | **[[3gen]], [[3ocs]], [[3pix]], [[3piy]], [[3piz]], [[3pj1]], [[3pj2]], [[3pj3]], [[4nwm]], [[4yhf]], [[5jrs]], [[5fbo]], [[5fbn]], [[4rx5]], [[5bpy]], [[5bq0]], [[5vgo]], [[5u9d]], [[5t18]], [[5p9m]], [[5p9l]], [[5p9m]], [[5p9l]], [[5p9f]], [[5p9g]], [[5p9h]], [[5p9i]], [[5p9j]], [[5p9k]], [[5vfi]], [[4z3v]], [[4zly]], [[4zlz]], [[5zz4]], [[6aua]], [[6aub]], [[5j87]], [[5xyz]], [[6bik]], [[6bke]], [[6bkh]], [[6bkw]], [[6bln]], [[6di0]], [[6di1]], [[6di3]], [[6di5]], [[6di9]], [[6e4f]], [[6e9p]], [[5kup]], [[6tfp]], [[6s90]], [[6o8i]], [[6nzm]], [[6nfi]], [[6nfh]], [[6n9p]] - hTK Btk kinase domain + inhibitor<br /> | + | **[[3gen]], [[3ocs]], [[3pix]], [[3piy]], [[3piz]], [[3pj1]], [[3pj2]], [[3pj3]], [[4nwm]], [[4yhf]], [[5jrs]], [[5fbo]], [[5fbn]], [[4rx5]], [[5bpy]], [[5bq0]], [[5vgo]], [[5u9d]], [[5t18]], [[5p9m]], [[5p9l]], [[5p9m]], [[5p9l]], [[5p9f]], [[5p9g]], [[5p9h]], [[5p9i]], [[5p9j]], [[5p9k]], [[5vfi]], [[4z3v]], [[4zly]], [[4zlz]], [[5zz4]], [[6aua]], [[6aub]], [[5j87]], [[5xyz]], [[6bik]], [[6bke]], [[6bkh]], [[6bkw]], [[6bln]], [[6di0]], [[6di1]], [[6di3]], [[6di5]], [[6di9]], [[6e4f]], [[6e9p]], [[5kup]], [[6tfp]], [[6s90]], [[6o8i]], [[6nzm]], [[6nfi]], [[6nfh]], [[6n9p]], [[6w07]], [[6w06]], [[6vxq]] - hTK Btk kinase domain + inhibitor<br /> |
**[[3k54]], [[3t9t]], [[4ot5]], [[4ot6]], [[4otq]], [[4otr]], [[4otf]], [[4rfy]], [[4rfz]], [[4rg0]], [[6ep9]], [[6hrt]], [[6hrp]] - hTK Btk kinase domain (mutant) + inhibitor<br /> | **[[3k54]], [[3t9t]], [[4ot5]], [[4ot6]], [[4otq]], [[4otr]], [[4otf]], [[4rfy]], [[4rfz]], [[4rg0]], [[6ep9]], [[6hrt]], [[6hrp]] - hTK Btk kinase domain (mutant) + inhibitor<br /> | ||
**[[5vgo]] - hTK Btk kinase domain + cancer drug<br /> | **[[5vgo]] - hTK Btk kinase domain + cancer drug<br /> | ||
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*Mer complex | *Mer complex | ||
| + | **[[7ab0]] - hTK Mer kinase domain<br /> | ||
**[[3brb]] - hTK Mer kinase domain + ADP<br /> | **[[3brb]] - hTK Mer kinase domain + ADP<br /> | ||
**[[2p0c]] - hTK Mer kinase domain + ANP<br /> | **[[2p0c]] - hTK Mer kinase domain + ANP<br /> | ||
**[[3bpr]], [[3tcp]], [[4m3q]], [[4mh7]], [[4mha]], [[5u6c]], [[5tc0]], [[5k0k]], [[5k0x]], [[5td2]], [[6mep]] - hTK Mer kinase domain + inhibitor<br /> | **[[3bpr]], [[3tcp]], [[4m3q]], [[4mh7]], [[4mha]], [[5u6c]], [[5tc0]], [[5k0k]], [[5k0x]], [[5td2]], [[6mep]] - hTK Mer kinase domain + inhibitor<br /> | ||
| + | **[[7ab2]], [[7aax]], [[7aaz]] - hTK Mer kinase domain (mutant) + inhibitor<br /> | ||
| + | **[[7ab1]] - hTK Mer kinase domain + anti-cancer drug<br /> | ||
| + | **[[7aay]] - hTK Mer kinase domain (mutant) + anti-cancer drug<br /> | ||
| - | *'''Bone marrow tyrosine kinase''' | + | *'''Bone marrow tyrosine kinase'''; Domains – kinase 411-675 |
**[[2ekx]] - hTK Bmx SH2 domain – NMR<BR /> | **[[2ekx]] - hTK Bmx SH2 domain – NMR<BR /> | ||
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*Bone marrow tyrosine kinase complex | *Bone marrow tyrosine kinase complex | ||
| - | **[[3sxr]] - hTK Bmx kinase domain (mutant) + | + | **[[3sxr]] - hTK Bmx kinase domain (mutant) + anti-cancer drug<br /> |
| - | **[[3sxs]] - hTK Bmx kinase domain (mutant) + inhibitor<br /> | + | **[[3sxs]], [[6i99]] - hTK Bmx kinase domain (mutant) + inhibitor<br /> |
*'''ErbB tyrosine kinase''' see [[Epidermal Growth Factor Receptor]] | *'''ErbB tyrosine kinase''' see [[Epidermal Growth Factor Receptor]] | ||
Revision as of 11:01, 27 December 2020
3D structures of tyrosine kinase
Updated on 27-December-2020 - For a general description of the protein see Tyrosine kinase
