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| - | | + | #REDIRECT [[7a62]] This PDB entry is obsolete and replaced by 7a62 |
| - | ==Structure of human indoleamine-2,3-dioxygenase 1 (hIDO) with a complete JK loop==
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| - | <StructureSection load='6tue' size='340' side='right'caption='[[6tue]], [[Resolution|resolution]] 2.61Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[6tue]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TUE FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </span></td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tue OCA], [http://pdbe.org/6tue PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tue RCSB], [http://www.ebi.ac.uk/pdbsum/6tue PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tue ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN]] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Indoleamine 2,3-dioxygenase]]
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| - | [[Category: Large Structures]]
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| - | [[Category: Mirgaux, M]]
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| - | [[Category: Wouters, J]]
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| - | [[Category: Dioxygenase]]
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| - | [[Category: Enzyme]]
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| - | [[Category: Heme-binding]]
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| - | [[Category: Oxidoreductase]]
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| - | [[Category: Tryptophan catabolism]]
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