Tyrosine kinase 3D structures

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*'''RECEPTOR TYROSINE KINASES - RTK'''
*'''RECEPTOR TYROSINE KINASES - RTK'''
 +
 +
*'''Bone marrow tyrosine kinase'''; Domains – kinase 411-675
 +
 +
**[[2ekx]] - hTK Bmx SH2 domain – NMR<BR />
 +
**[[2ys2]] - hTK Bmx Btk motif – NMR<BR />
 +
 +
*Bone marrow tyrosine kinase complex
 +
 +
**[[3sxr]] - hTK Bmx kinase domain (mutant) + anti-cancer drug<br />
 +
**[[3sxs]], [[6i99]] - hTK Bmx kinase domain (mutant) + inhibitor<br />
*'''Bruton’s tyrosine kinase Btk''' (Domains: PH 1-170; SH3 216-273; SH2 273-378; kinase 378-659)
*'''Bruton’s tyrosine kinase Btk''' (Domains: PH 1-170; SH3 216-273; SH2 273-378; kinase 378-659)
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**[[4y94]] - bTK Btk kinase domain + inhibitor<br />
**[[4y94]] - bTK Btk kinase domain + inhibitor<br />
**[[6mny]] - mTK Btk kinase domain + inhibitor<br />
**[[6mny]] - mTK Btk kinase domain + inhibitor<br />
 +
 +
*'''Cbl-c tyrosine kinase''' or '''signal transduction protein Cbl-c'''
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 +
**[[3vrn]] - hTK Cbl-c kinase domain <br />
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**[[3vrq]] - hTK Cbl-c kinase domain (mutant)<br />
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**[[3vro]] - hTK Cbl-c kinase domain + Src peptide<br />
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**[[3vrp]] - hTK Cbl-c kinase domain + EGRF peptide<br />
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**[[3vrr]] - hTK Cbl-c kinase domain (mutant) + EGRF peptide<br />
 +
**[[3op0]] - hTK Cbl-c N-terminal domain (mutant) + EGRF peptide<br />
*'''c-FMS tyrosine kinase or macrophage colony-stimulating factor 1 receptor''' see [[Colony-stimulating factor receptor]]
*'''c-FMS tyrosine kinase or macrophage colony-stimulating factor 1 receptor''' see [[Colony-stimulating factor receptor]]
*'''DDR1 and DDR2 tyrosine kinase receptors''' see [[Epithelial discoidin domain-containing receptor]]
*'''DDR1 and DDR2 tyrosine kinase receptors''' see [[Epithelial discoidin domain-containing receptor]]
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 +
*'''ErbB tyrosine kinase''' see [[Epidermal Growth Factor Receptor]]
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*'''Flt3 tyrosine kinase'''; Domains - kinase 564-958
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**[[1rjb]] - hTK Flt3 kinase domain <br />
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**[[4rt7]], [[6il3]], [[5x02]] - hTK Flt3 kinase domain + inhibitor<br />
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**[[4xuf]], [[6jqr]] - hTK Flt3 kinase domain (mutant) + leukemia drug<br />
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**[[3qs9]], [[3qs7]] - hTK Flt3 residues 27-540 + SL cytokine <br />
*'''Kit tyrosine kinase''' or '''mast/stem cell growth factor receptor Kit'''; Domains – extracellular 1-519; kinase 547-693, 754-935
*'''Kit tyrosine kinase''' or '''mast/stem cell growth factor receptor Kit'''; Domains – extracellular 1-519; kinase 547-693, 754-935
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**[[2o26]] - hTK Kit residues 25-314 + Kit ligand<br />
**[[2o26]] - hTK Kit residues 25-314 + Kit ligand<br />
**[[4k94]], [[4k9e]] - hTK Kit residues 308-518 + antibody<br />
**[[4k94]], [[4k9e]] - hTK Kit residues 308-518 + antibody<br />
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 +
*'''Matk tyrosine kinase''' or '''megakaryocyte-associated tyrosine-protein kinase'''
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**[[3us4]] - hTK Matk SH2 domain <br />
*'''Mer tyrosine kinase (Domains: FN3 373-483; kinase 570-864)'''
*'''Mer tyrosine kinase (Domains: FN3 373-483; kinase 570-864)'''
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**[[7aay]] - hTK Mer kinase domain (mutant) + anti-cancer drug<br />
**[[7aay]] - hTK Mer kinase domain (mutant) + anti-cancer drug<br />
-
*'''Bone marrow tyrosine kinase'''; Domains – kinase 411-675
+
*'''c-Met tyrosine kinase''' see [[Hepatocyte growth factor receptor]]
-
 
+
-
**[[2ekx]] - hTK Bmx SH2 domain – NMR<BR />
+
-
**[[2ys2]] - hTK Bmx Btk motif – NMR<BR />
+
-
 
+
-
*Bone marrow tyrosine kinase complex
+
-
 
+
-
**[[3sxr]] - hTK Bmx kinase domain (mutant) + anti-cancer drug<br />
+
-
**[[3sxs]], [[6i99]] - hTK Bmx kinase domain (mutant) + inhibitor<br />
+
-
 
+
-
*'''ErbB tyrosine kinase''' see [[Epidermal Growth Factor Receptor]]
+
*'''MuSK tyrosine kinase''' or '''muscle skeleton receptor tyrosine kinase'''
*'''MuSK tyrosine kinase''' or '''muscle skeleton receptor tyrosine kinase'''
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**[[3hkl]] - rTK MuSK Fz-Crd domain <br />
**[[3hkl]] - rTK MuSK Fz-Crd domain <br />
**[[1luf]], [[2iep]] - rTK MuSK cytoplasmic domain <br />
**[[1luf]], [[2iep]] - rTK MuSK cytoplasmic domain <br />
- 
-
*'''Sgk223 tyrosine kinase or sugen kinase'''
 
- 
-
**[[5ve6]] - hTK <br />
 
- 
-
*'''Matk tyrosine kinase''' or '''megakaryocyte-associated tyrosine-protein kinase'''
 
- 
-
**[[3us4]] - hTK Matk SH2 domain <br />
 
- 
-
*'''Cbl-c tyrosine kinase''' or '''signal transduction protein Cbl-c'''
 
- 
-
**[[3vrn]] - hTK Cbl-c kinase domain <br />
 
-
**[[3vrq]] - hTK Cbl-c kinase domain (mutant)<br />
 
-
**[[3vro]] - hTK Cbl-c kinase domain + Src peptide<br />
 
-
**[[3vrp]] - hTK Cbl-c kinase domain + EGRF peptide<br />
 
-
**[[3vrr]] - hTK Cbl-c kinase domain (mutant) + EGRF peptide<br />
 
-
**[[3op0]] - hTK Cbl-c N-terminal domain (mutant) + EGRF peptide<br />
 
- 
-
*'''Flt3 tyrosine kinase'''; Domains - kinase 564-958
 
- 
-
**[[1rjb]] - hTK Flt3 kinase domain <br />
 
-
**[[4rt7]], [[6il3]], [[5x02]] - hTK Flt3 kinase domain + inhibitor<br />
 
-
**[[4xuf]], [[6jqr]] - hTK Flt3 kinase domain (mutant) + leukemia drug<br />
 
-
**[[3qs9]], [[3qs7]] - hTK Flt3 residues 27-540 + SL cytokine <br />
 
- 
-
*'''Tie2 tyrosine kinase'''
 
- 
-
**[[1fvr]] - hTK Tie2 kinase domain <br />
 
*'''Ret tyrosine kinase''' or '''proto-oncogene tyrosine protein kinase receptor Ret'''
*'''Ret tyrosine kinase''' or '''proto-oncogene tyrosine protein kinase receptor Ret'''
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**[[6osv]], [[6osh]] - hTK ROR2 Kringle domain + antibody<br />
**[[6osv]], [[6osh]] - hTK ROR2 Kringle domain + antibody<br />
-
*'''c-Met tyrosine kinase''' see [[Hepatocyte growth factor receptor]]
+
*'''Sgk223 tyrosine kinase or sugen kinase'''
 +
 
 +
**[[5ve6]] - hTK <br />
 +
 
 +
*'''Tie2 tyrosine kinase'''
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**[[1fvr]] - hTK Tie2 kinase domain <br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:04, 30 December 2020

3D structures of tyrosine kinase

Updated on 30-December-2020 - For a general description of the protein see Tyrosine kinase

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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