Ubiquitin

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Line 86: Line 86:
* Polyubiquitin-B
* Polyubiquitin-B
 +
**[[6nxl]] – hUBB<br />
**[[4zpz]] – hUBB (mutant)<br />
**[[4zpz]] – hUBB (mutant)<br />
**[[5x3o]], [[3x3m]] – hUBB + d-ubiquitin <br />
**[[5x3o]], [[3x3m]] – hUBB + d-ubiquitin <br />
Line 120: Line 121:
**[[3ofi]] – hUBB+insulin protease
**[[3ofi]] – hUBB+insulin protease
 +
**[[3i3t]], [[2ibi]], [[2ayo]], [[1nbf]], [[2wdt]], [[4i6l]], [[4i6n]], [[4ig7]], [[5l8h]], [[5jtj]], [[5cvm]], [[6crn]] - hUBB+hUBB carboxyl-terminal hydrolase catalytic domain<br />
**[[3n3k]], [[3ifw]], [[3kvf]], [[3kw5]], [[3irt]], [[3mtn]], [[3ihp]], [[3v6c]], [[3v6e]]– hUBB (mutant)+hUBB carboxyl-terminal esterase catalytic domain<br />
**[[3n3k]], [[3ifw]], [[3kvf]], [[3kw5]], [[3irt]], [[3mtn]], [[3ihp]], [[3v6c]], [[3v6e]]– hUBB (mutant)+hUBB carboxyl-terminal esterase catalytic domain<br />
-
**[[3i3t]], [[2ibi]], [[2ayo]], [[1nbf]], [[2wdt]], [[4i6l]], [[4i6n]], [[4ig7]], [[5l8h]], [[5jtj]], [[5cvm]] - hUBB+hUBB carboxyl-terminal hydrolase catalytic domain<br />
 
**[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + UBB carboxy terminal hydrolase 12 + WD repeat containing protein 48<br />
**[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + UBB carboxy terminal hydrolase 12 + WD repeat containing protein 48<br />
**[[2khw]] – hUBB+immunoglobulin G-binding protein G<br />
**[[2khw]] – hUBB+immunoglobulin G-binding protein G<br />
Line 173: Line 174:
**[[4un2]] – hUBB + Dsk2 peptide<br />
**[[4un2]] – hUBB + Dsk2 peptide<br />
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
**[[4msq]], [[4msm]] – hUBB + AMSH-like protease<br />
 +
**[[6upu]] – hUBB + otDUB<br />
**[[4m0w]] – bUBB + replicase polyprotein<br />
**[[4m0w]] – bUBB + replicase polyprotein<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
Line 184: Line 186:
**[[1wr6]], [[1yd8]] - bUBB+GGA3 GAT domain<br />
**[[1wr6]], [[1yd8]] - bUBB+GGA3 GAT domain<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
**[[1uzx]] – bUBB+VPS23 UEV<br />
 +
**[[4nql]] – mUBB + AMSH-like protease<br />
**[[2kdi]] – yUBB/UIM fusion <br />
**[[2kdi]] – yUBB/UIM fusion <br />
**[[2jt4]] – yUBB fragment+cytoskeleton assembly control protein<br />
**[[2jt4]] – yUBB fragment+cytoskeleton assembly control protein<br />
Line 191: Line 194:
**[[1otr]] – yUBB+CUE2<br />
**[[1otr]] – yUBB+CUE2<br />
**[[2l00]] – yUBB + Zfand5<br />
**[[2l00]] – yUBB + Zfand5<br />
-
**[[4nql]] – mUBB + AMSH-like protease<br />
 
* Ubiquitin complex with ubiquitination enzymes
* Ubiquitin complex with ubiquitination enzymes
-
**[[1fxt]], [[3oj4]], [[3ugb]], [[5dfl]], [[3k9p]], [[3a33]], [[5ulf]], [[5tut]] – hUBB + UBB conjugating enzyme E2<br />
+
**[[1fxt]], [[3oj4]], [[3ugb]], [[5dfl]], [[3k9p]], [[3a33]], [[5ulf]], [[5tut]], [[6nyo]] – hUBB + UBB conjugating enzyme E2<br />
-
**[[5bnb]], [[2kjh]], [[1zgu]] – hUBB (mutant) + UBB conjugating enzyme E2<br />
+
**[[5bnb]], [[2kjh]], [[1zgu]], [[6d4p]] – hUBB (mutant) + UBB conjugating enzyme E2<br />
**[[5edv]], [[4whv]], [[5ait]], [[5aiu]], [[3jvz]], [[3jw0]], [[5udh]], [[5tte]] – hUBB + UBB conjugating enzyme E2 + E3 UBB-protein ligase<br />
**[[5edv]], [[4whv]], [[5ait]], [[5aiu]], [[3jvz]], [[3jw0]], [[5udh]], [[5tte]] – hUBB + UBB conjugating enzyme E2 + E3 UBB-protein ligase<br />
-
**[[3cmm]] – yUBB + UBB activating enzyme E1<br />
 
-
**[[5knl]] – yUBB (mutant) + UBB activating enzyme E1 + UBB conjugating enzyme E2 <br />
 
-
**[[5tr4]] – bUBB + UBB activating enzyme E1<br />
 
**[[2gmi]] – hUBB + UBB conjugating enzyme E2<br />
**[[2gmi]] – hUBB + UBB conjugating enzyme E2<br />
**[[2fuh]] – hUBB + UBB conjugating enzyme E2 - NMR<br />
**[[2fuh]] – hUBB + UBB conjugating enzyme E2 - NMR<br />
Line 208: Line 207:
**[[5o76]] – hUBB + Zap70 peptide + E3-UBB-protein ligase CBL<br />
**[[5o76]] – hUBB + Zap70 peptide + E3-UBB-protein ligase CBL<br />
**[[4auq]] – hUBB + UBB conjugating enzyme E2 + livin<br />
**[[4auq]] – hUBB + UBB conjugating enzyme E2 + livin<br />
 +
**[[5tr4]] – bUBB + UBB activating enzyme E1<br />
 +
**[[6djw]], [[6djx]] – bUBB + UBB activating enzyme E2 + parkin<br />
 +
**[[6nya]] – UBB (mutant) + yUBB activating enzyme E1 + yUBB conjugating enzyme E2 - wheat <br />
**[[4q5h]], [[4q5e]] – yUBB + UBB conjugating enzyme E2 + OspG<br />
**[[4q5h]], [[4q5e]] – yUBB + UBB conjugating enzyme E2 + OspG<br />
 +
**[[3cmm]] – yUBB + UBB activating enzyme E1<br />
 +
**[[5knl]] – yUBB (mutant) + UBB activating enzyme E1 + UBB conjugating enzyme E2 <br />
* Ubiquitin + ions
* Ubiquitin + ions

Revision as of 11:04, 31 December 2020

Human ubiquitin (green) complex with ubiquitin-conjugating enzyme E2 (deep sky blue), 3k9p

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3D Structures of Ubiquitin

Updated on 31-December-2020

References

  1. Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem. 1998;67:425-79. PMID:9759494 doi:http://dx.doi.org/10.1146/annurev.biochem.67.1.425
  2. Paul S. Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches. Bioessays. 2008 Nov;30(11-12):1172-84. doi: 10.1002/bies.20852. PMID:18937370 doi:http://dx.doi.org/10.1002/bies.20852
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