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TRAP dicarboxylate transporter, DctP subunit
From Proteopedia
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| - | <StructureSection load=' | + | <StructureSection load='4mhf' size='340' side='right' caption='DctP complex with glucuronate (PDB code [[4mhf]])' scene=''> |
==Function== | ==Function== | ||
| - | '''TRAP dicarboxylate transporter, DctP subunit''' | + | '''TRAP dicarboxylate transporter, DctP subunit''' is part of the tripartite ATP-dependent transporters which consist of three protiens: DctP, DctM and DctQ. DctP is a periplasmic C4-dicarboxylate-binding receptor<ref>PMID:10627041</ref>. |
| - | <ref>PMID: | + | |
== Disease == | == Disease == | ||
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| - | RPE1 has been shown to mitigate host cell defenses leading to the development of cancer induces apoptosis of its host cells<ref>PMID:29495005</ref>. | ||
==Relevance== | ==Relevance== | ||
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| - | The detection of RPE1 mRNA and promoter methylation may serve as cancer prognostic marker. | ||
== Structural highlights == | == Structural highlights == | ||
| - | The complex between BPV1 DBD and 21-bp DNA (PDB code [[1ksx]]) shows 2 DBD-DNA binding modules: a binding loop and a binding helix each interacting with a single strand. The protein-DNA interactions are hydrophilic to phosphate atoms and van der Waals hydrophobic ones<ref>PMID:11889054</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of TRAP dicarboxylate transporter, DctP subunit== | ==3D structures of TRAP dicarboxylate transporter, DctP subunit== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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| + | *TRAP dicarboxylate transporter, DctP subunit | ||
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| + | **[[4pfi]] - DctP - ''Marinobacter hydrocarbonoclasticus''<br /> | ||
| + | **[[4pe3]] - RsDctP - ''Rhodobacter sphaeroides''<br /> | ||
| + | **[[4p1e]] - DctP - ''Escherichia fergusonii''<br /> | ||
| + | **[[4p47]] - OaDctP - ''Ochtrobactrum anthropi''<br /> | ||
| + | **[[4n6d]] - DsDctP - ''Desulfovibrio salexigens''<br /> | ||
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| + | *TRAP dicarboxylate transporter, DctP subunit complex with glucuronate derivative | ||
| - | + | **[[4n91]] - DctP + glucuronate - ''Anaerococcus prevotii''<br /> | |
| + | **[[4ovq]] - DctP + glucuronate - ''Roeobacter denitrificans''<br /> | ||
| + | **[[4ovr]] - DctP + galacturonate - ''Xanthobacter autotrophicus''<br /> | ||
| + | **[[4mig]] - PoDctP + galacturonate - ''Polaromonas''<br /> | ||
| + | **[[4mhf]] - PoDctP + glucuronate <br /> | ||
| + | **[[4p1l]], [[4p3l]] - CsDctP + glucuronate <br /> | ||
| + | **[[4x8r]] - RsDctP + glucuronate <br /> | ||
| + | **[[4xfe]] - DctP + glucuronate - ''Pseudomonas putida''<br /> | ||
| + | **[[4n15]] - BaDctP + glucuronate - ''Burkholderia ambifaria''<br /> | ||
| + | **[[4n17]] - BaDctP + galacturonate <br /> | ||
| - | + | *TRAP dicarboxylate transporter, DctP subunit other complexes | |
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| + | **[[4n6k]] - DsDctP + diglycerolphosphate<br /> | ||
| + | **[[4nn3]] - DsDctP + orotate<br /> | ||
| + | **[[4nhb]] - DctP + glycerolphosphate - ''Desulfovibrio desulfuricans''<br /> | ||
| + | **[[4ngu]] - DctP + Ala-Ala - ''Desulfovibrio alaskensis''<br /> | ||
| + | **[[4xeq]] - DctP + pantoate - ''Desulfovibrio vulgaris''<br /> | ||
| + | **[[4mco]], [[4mev]] - DctP + malonate - ''Rhodoferax ferrireducens''<br /> | ||
| + | **[[4ovt]] - OaDctP + fuconate<br /> | ||
| + | **[[5cm6]] - DctP + pyruvate - ''Pseudoalteromonas atlantica''<br /> | ||
| + | **[[4pdd]], [[4pdh]] - PoDctP + erythronate <br /> | ||
| + | **[[4mnc]], [[4mni]] - PoDctP + benzoyl formate <br /> | ||
| + | **[[4n8g]] - CsDctP + Ala-Ala - ''Chromohalobacter salexigens''<br /> | ||
| + | **[[4ovs]] - DctP + succinate - ''Sulfurospirillum deleyianum''<br /> | ||
| + | **[[4o94]] - RpDctP + succinate - ''Rhodopseudomonas palustris''<br /> | ||
| + | **[[4oan]] - RpDctP + acetolactate derivative<br /> | ||
| + | **[[4paf]], [[4pai]], [[4pbh]] - DctP + benzoate derivative - ''Ruegeria pomeroyi''<br /> | ||
| + | **[[4pfr]] - RsDctP + malate<br /> | ||
| + | **[[4o7m]] - SlDctP + malate - ''Shewanella loihica''<br /> | ||
| + | **[[4oa4]] - SlDctP + succinate <br /> | ||
| + | **[[4ln5]] - BaDctP + glycerol <br /> | ||
| + | **[[3fxb]] - DctP + ectoine - ''Silicibacter pomeroyi''<br /> | ||
| + | **[[4o8m]] - RsDctP + galactonate - ''Actinobacillus succinogenes''<br /> | ||
| + | **[[4p9k]] - ewDctP + erythronate - earthworm<br /> | ||
| + | **[[4pak]] - ewDctP + pantoate<br /> | ||
| + | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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3D structures of TRAP dicarboxylate transporter, DctP subunit
Updated on 01-February-2021
References
- ↑ Rabus R, Jack DL, Kelly DJ, Saier MH Jr. TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters. Microbiology (Reading). 1999 Dec;145 ( Pt 12):3431-3445. doi:, 10.1099/00221287-145-12-3431. PMID:10627041 doi:http://dx.doi.org/10.1099/00221287-145-12-3431
