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2dgo
From Proteopedia
(Difference between revisions)
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==Solution structure of the RNA binding domain in cytotoxic granule-associated RNA binding protein 1== | ==Solution structure of the RNA binding domain in cytotoxic granule-associated RNA binding protein 1== | ||
| - | <StructureSection load='2dgo' size='340' side='right' caption='[[2dgo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2dgo' size='340' side='right'caption='[[2dgo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dgo]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dgo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DGO FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tia1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tia1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dgo OCA], [https://pdbe.org/2dgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dgo RCSB], [https://www.ebi.ac.uk/pdbsum/2dgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dgo ProSAT], [https://www.topsan.org/Proteins/RSGI/2dgo TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TIA1_MOUSE TIA1_MOUSE]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Abe, C]] | [[Category: Abe, C]] | ||
Revision as of 12:01, 3 February 2021
Solution structure of the RNA binding domain in cytotoxic granule-associated RNA binding protein 1
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