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2dzv

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==Structure of mutant tryptophan synthase alpha-subunit (D146A) from a hyperthermophile, Pyrococcus furiosus==
==Structure of mutant tryptophan synthase alpha-subunit (D146A) from a hyperthermophile, Pyrococcus furiosus==
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<StructureSection load='2dzv' size='340' side='right' caption='[[2dzv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='2dzv' size='340' side='right'caption='[[2dzv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DZV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dzv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZV FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1geq|1geq]], [[2dzp|2dzp]], [[2dzs|2dzs]], [[2dzt|2dzt]], [[2dzu|2dzu]], [[2dzw|2dzw]], [[2dzx|2dzx]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1geq|1geq]], [[2dzp|2dzp]], [[2dzs|2dzs]], [[2dzt|2dzt]], [[2dzu|2dzu]], [[2dzw|2dzw]], [[2dzx|2dzx]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzv OCA], [http://pdbe.org/2dzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dzv RCSB], [http://www.ebi.ac.uk/pdbsum/2dzv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzv ProSAT], [http://www.topsan.org/Proteins/RSGI/2dzv TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzv OCA], [https://pdbe.org/2dzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzv RCSB], [https://www.ebi.ac.uk/pdbsum/2dzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzv ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzv TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRPA_PYRFU TRPA_PYRFU]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
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[[https://www.uniprot.org/uniprot/TRPA_PYRFU TRPA_PYRFU]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Tryptophan synthase|Tryptophan synthase]]
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*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Atcc 43587]]
[[Category: Atcc 43587]]
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[[Category: Large Structures]]
[[Category: Tryptophan synthase]]
[[Category: Tryptophan synthase]]
[[Category: Ogasahara, K]]
[[Category: Ogasahara, K]]

Revision as of 11:43, 10 February 2021

Structure of mutant tryptophan synthase alpha-subunit (D146A) from a hyperthermophile, Pyrococcus furiosus

PDB ID 2dzv

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