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2e3g
From Proteopedia
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==NMR structure of DEF-DAA, a mutant of anopheles defensin DEF-AAA== | ==NMR structure of DEF-DAA, a mutant of anopheles defensin DEF-AAA== | ||
| - | <StructureSection load='2e3g' size='340' side='right' caption='[[2e3g]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | + | <StructureSection load='2e3g' size='340' side='right'caption='[[2e3g]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e3g]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2e3g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anoga Anoga]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E3G FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ny8|2ny8]], [[2ny9|2ny9]], [[2nz3|2nz3]], [[2e3e|2e3e]], [[2e3f|2e3f]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ny8|2ny8]], [[2ny9|2ny9]], [[2nz3|2nz3]], [[2e3e|2e3e]], [[2e3f|2e3f]]</div></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DEF1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DEF1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7165 ANOGA])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e3g OCA], [https://pdbe.org/2e3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e3g RCSB], [https://www.ebi.ac.uk/pdbsum/2e3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e3g ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DEFI_ANOGA DEFI_ANOGA]] Responsible for the anti Gram-positive activity of immune hemolymph (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3g_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3g_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e3g ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2e3g" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Defensin|Defensin]] | + | *[[Defensin 3D structures|Defensin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Anoga]] |
| - | [[Category: Barbault, F | + | [[Category: Large Structures]] |
| - | [[Category: Landon, C | + | [[Category: Barbault, F]] |
| - | [[Category: Vovelle, F | + | [[Category: Landon, C]] |
| + | [[Category: Vovelle, F]] | ||
[[Category: Antibacterial]] | [[Category: Antibacterial]] | ||
[[Category: Antimicrobial protein]] | [[Category: Antimicrobial protein]] | ||
[[Category: Csab motif]] | [[Category: Csab motif]] | ||
[[Category: Insect defensin]] | [[Category: Insect defensin]] | ||
Current revision
NMR structure of DEF-DAA, a mutant of anopheles defensin DEF-AAA
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