This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2e3v
From Proteopedia
(Difference between revisions)
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2e3v.jpg|left|200px]]<br /><applet load="2e3v" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2e3v, resolution 1.95Å" /> | ||
| - | '''Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4'''<br /> | ||
| - | == | + | ==Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4== |
| - | + | <StructureSection load='2e3v' size='340' side='right'caption='[[2e3v]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2e3v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E3V FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| - | [ | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2haz|2haz]]</div></td></tr> |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NCAM1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e3v OCA], [https://pdbe.org/2e3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e3v RCSB], [https://www.ebi.ac.uk/pdbsum/2e3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e3v ProSAT], [https://www.topsan.org/Proteins/RSGI/2e3v TOPSAN]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [[https://www.uniprot.org/uniprot/NCAM1_HUMAN NCAM1_HUMAN]] This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. |
| - | [[Category: | + | == Evolutionary Conservation == |
| - | [[Category: | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: | + | Check<jmol> |
| - | [[Category: | + | <jmolCheckbox> |
| - | [[Category: | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e3v_consurf.spt"</scriptWhenChecked> |
| - | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: | + | </jmolCheckbox> |
| - | [[Category: | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e3v ConSurf]. |
| - | [[Category: | + | <div style="clear:both"></div> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Human]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Chen, L]] |
| - | + | [[Category: Kishishita, S]] | |
| - | + | [[Category: Liu, Z J]] | |
| - | + | [[Category: Nishino, A]] | |
| - | + | [[Category: Structural genomic]] | |
| + | [[Category: Saijo, S]] | ||
| + | [[Category: Shirouzu, M]] | ||
| + | [[Category: Wang, B C]] | ||
| + | [[Category: Yokoyama, S]] | ||
| + | [[Category: Cd56 antigen]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: N-cam 1]] | ||
| + | [[Category: National project on protein structural and functional analyse]] | ||
| + | [[Category: Ncam]] | ||
| + | [[Category: Ncam-120]] | ||
| + | [[Category: Nppsfa]] | ||
| + | [[Category: Rsgi]] | ||
Current revision
Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4
| |||||||||||
Categories: Human | Large Structures | Chen, L | Kishishita, S | Liu, Z J | Nishino, A | Structural genomic | Saijo, S | Shirouzu, M | Wang, B C | Yokoyama, S | Cd56 antigen | Cell adhesion | Glycoprotein | Membrane protein | N-cam 1 | National project on protein structural and functional analyse | Ncam | Ncam-120 | Nppsfa | Rsgi
