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2eob
From Proteopedia
(Difference between revisions)
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==Solution structure of the second SH2 domain from rat PLC gamma-2== | ==Solution structure of the second SH2 domain from rat PLC gamma-2== | ||
| - | <StructureSection load='2eob' size='340' side='right' caption='[[2eob]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2eob' size='340' side='right'caption='[[2eob]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2eob]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2eob]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EOB FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Plcg2 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Plcg2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphoinositide_phospholipase_C Phosphoinositide phospholipase C], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.11 3.1.4.11] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eob OCA], [https://pdbe.org/2eob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eob RCSB], [https://www.ebi.ac.uk/pdbsum/2eob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eob ProSAT], [https://www.topsan.org/Proteins/RSGI/2eob TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PLCG2_RAT PLCG2_RAT]] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Buffalo rat]] | [[Category: Buffalo rat]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Phosphoinositide phospholipase C]] | [[Category: Phosphoinositide phospholipase C]] | ||
[[Category: Hayashi, F]] | [[Category: Hayashi, F]] | ||
Revision as of 12:19, 10 February 2021
Solution structure of the second SH2 domain from rat PLC gamma-2
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Categories: Buffalo rat | Large Structures | Phosphoinositide phospholipase C | Hayashi, F | Nagashima, T | Structural genomic | Sano, R | Yokoyama, S | Yoshida, M | Hydrolase | National project on protein structural and functional analyse | Nppsfa | Phosphoinositide phospholipase c | Phospholipase c-gamma-2 | Plc-gamma-2 | Plc-iv | Rsgi | Sh2
