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2f2e
From Proteopedia
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| - | [[Image:2f2e.gif|left|200px]] | ||
| - | + | ==Crystal Structure of PA1607, a Putative Transcription Factor== | |
| - | + | <StructureSection load='2f2e' size='340' side='right'caption='[[2f2e]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | | | + | <table><tr><td colspan='2'>[[2f2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2E FirstGlance]. <br> |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | | | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA1607 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2e OCA], [https://pdbe.org/2f2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2e RCSB], [https://www.ebi.ac.uk/pdbsum/2f2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2e ProSAT], [https://www.topsan.org/Proteins/MCSG/2f2e TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f2e_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f2e ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The structure of the PA1607 protein from Pseudomonas aureginosa was determined at 1.85 A resolution using the Se-Met multiwavelength anomalous diffraction (MAD) technique. PA1607 forms a dimer and adopts a winged-helix motif similar to the MarR family of transcription regulators, though it has an unusual dimerization profile. The DNA-binding regions and a putative metal-binding site are not conserved in PA1607. | ||
| - | + | The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor.,Sieminska EA, Xu X, Savchenko A, Sanders DA Protein Sci. 2007 Mar;16(3):543-9. PMID:17322537<ref>PMID:17322537</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 2f2e" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Cuff, M | + | __TOC__ |
| - | [[Category: Edwards, A | + | </StructureSection> |
| - | [[Category: Joachimiak, A | + | [[Category: Large Structures]] |
| - | [[Category: Lunin, V | + | [[Category: Cuff, M]] |
| - | [[Category: | + | [[Category: Edwards, A]] |
| - | [[Category: Sanders, D A | + | [[Category: Joachimiak, A]] |
| - | [[Category: Savchenko, A | + | [[Category: Lunin, V]] |
| - | [[Category: Sieminska, E A | + | [[Category: Structural genomic]] |
| - | [[Category: Xu, X | + | [[Category: Sanders, D A]] |
| - | [[Category: Zheng, H | + | [[Category: Savchenko, A]] |
| - | [[Category: | + | [[Category: Sieminska, E A]] |
| - | [[Category: | + | [[Category: Xu, X]] |
| - | [[Category: | + | [[Category: Zheng, H]] |
| - | [[Category: | + | [[Category: Apc5613]] |
| - | + | [[Category: Helix-trun-helix]] | |
| - | [[Category: | + | [[Category: Mcsg]] |
| - | + | [[Category: PSI, Protein structure initiative]] | |
| - | + | [[Category: Transcription factor]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of PA1607, a Putative Transcription Factor
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