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2gcy
From Proteopedia
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| - | [[Image:2gcy.gif|left|200px]]<br /><applet load="2gcy" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2gcy, resolution 2.50Å" /> | ||
| - | '''humanized antibody C25 Fab fragment'''<br /> | ||
| - | == | + | ==humanized antibody C25 Fab fragment== |
| - | + | <StructureSection load='2gcy' size='340' side='right'caption='[[2gcy]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2gcy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GCY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">humanized mouse gene ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gcy OCA], [https://pdbe.org/2gcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gcy RCSB], [https://www.ebi.ac.uk/pdbsum/2gcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gcy ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | [[ | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/2gcy_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gcy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Antibody 3D structures|Antibody 3D structures]] | ||
| + | *[[Sandbox 20009|Sandbox 20009]] | ||
| + | *[[3D structures of non-human antibody|3D structures of non-human antibody]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lk3 transgenic mice]] | ||
| + | [[Category: Finer-Moore, J]] | ||
| + | [[Category: Forsyth, C M]] | ||
| + | [[Category: LaPorte, S L]] | ||
| + | [[Category: Marks, J D]] | ||
| + | [[Category: Antibody fragment mouse humanized]] | ||
| + | [[Category: Immune system]] | ||
Current revision
humanized antibody C25 Fab fragment
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