This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Aldose reductase 3D structures
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 10: | Line 10: | ||
**[[1xgd]] – hAldR (mutant)<br /> | **[[1xgd]] – hAldR (mutant)<br /> | ||
**[[3q67]] – hAldR (mutant)+NADP<br /> | **[[3q67]] – hAldR (mutant)+NADP<br /> | ||
| - | **[[3afm]] – SsAldR A1-R – ''Sphingomonas sp.''<br /> | ||
| - | **[[3afn]] - SsAldR A1-R+NADP<br /> | ||
**[[1dla]], [[1cwn]] – pAldR - pig<br /> | **[[1dla]], [[1cwn]] – pAldR - pig<br /> | ||
**[[1ah4]], [[3cv7]] - pAldR+NADP<br /> | **[[1ah4]], [[3cv7]] - pAldR+NADP<br /> | ||
**[[1hqt]] – pAldR (mutant) + NADP<br /> | **[[1hqt]] – pAldR (mutant) + NADP<br /> | ||
| - | **[[ | + | **[[4gca]] – AldR – mouse<br /> |
**[[2bgq]] – bAldR - barley<br /> | **[[2bgq]] – bAldR - barley<br /> | ||
**[[2bgs]] - bAldR+NADP<br /> | **[[2bgs]] - bAldR+NADP<br /> | ||
| - | **[[4gca]] – AldR – mouse<br /> | ||
**[[5jh1]], [[5jgy]] – maAldR – maize<br /> | **[[5jh1]], [[5jgy]] – maAldR – maize<br /> | ||
**[[5jgw]] – maAldR + NADP<br /> | **[[5jgw]] – maAldR + NADP<br /> | ||
**[[5zci]] – DnAldR – ''Debaryomyces nepalensis''<br /> | **[[5zci]] – DnAldR – ''Debaryomyces nepalensis''<br /> | ||
**[[5zcm]] – DnAldR + NADP<br /> | **[[5zcm]] – DnAldR + NADP<br /> | ||
| + | **[[3afm]] – SsAldR A1-R – ''Sphingomonas sp.''<br /> | ||
| + | **[[3afn]] - SsAldR A1-R+NADP<br /> | ||
| + | **[[3krb]] – AldR+NADP – ''Ghiardia lamblia''<br /> | ||
*Aldose Reductase+inhibitors | *Aldose Reductase+inhibitors | ||
| Line 33: | Line 33: | ||
**[[5ha7]] – hAldR (mutant) +NADP+pyrimidine inhibitor<br /> | **[[5ha7]] – hAldR (mutant) +NADP+pyrimidine inhibitor<br /> | ||
**[[4yu1]], [[4prt]], [[4prr]], [[4pr4]], [[4nkc]] – hAldR +NADP+ diphenyl inhibitor<br /> | **[[4yu1]], [[4prt]], [[4prr]], [[4pr4]], [[4nkc]] – hAldR +NADP+ diphenyl inhibitor<br /> | ||
| + | **[[5ouj]], [[5ouk]] – hAldR + NADP+ quinoine inhibitor<br /> | ||
**[[2pdg]], [[2pdh]], [[4xzi]], [[4xzh]] - hAldR+NADP+uracil inhibitor<br /> | **[[2pdg]], [[2pdh]], [[4xzi]], [[4xzh]] - hAldR+NADP+uracil inhibitor<br /> | ||
| - | **[[1x96]], [[2acs]], [[2acu]] - hAldR+NADP+citrate<br /> | + | **[[1x96]], [[2acs]], [[2acu]], [[6f7r]], [[6f81]], [[6f82]], [[6f84]], [[6f8o]] - hAldR+NADP+citrate<br /> |
**[[2acq]] - hAldR +NADP+glucose phosphate<br /> | **[[2acq]] - hAldR +NADP+glucose phosphate<br /> | ||
**[[2acr]] - hAldR +NADP+cacodylate<br /> | **[[2acr]] - hAldR +NADP+cacodylate<br /> | ||
| Line 45: | Line 46: | ||
**[[2pdn]], [[2pdq]] – hAldR (mutant)+NADP+uracil inhibitor<br /> | **[[2pdn]], [[2pdq]] – hAldR (mutant)+NADP+uracil inhibitor<br /> | ||
**[[2pdb]], [[2pdf]], [[2pdi]], [[2pdm]], [[2pdx]], [[3len]], [[3m0i]], [[3mb9]], [[2pd9]], [[2pdw]], [[2pdy]], [[2agt]], [[2pdl]] – hAldR (mutant)+NADP+inhibitor for diabetic treatment<br /> | **[[2pdb]], [[2pdf]], [[2pdi]], [[2pdm]], [[2pdx]], [[3len]], [[3m0i]], [[3mb9]], [[2pd9]], [[2pdw]], [[2pdy]], [[2agt]], [[2pdl]] – hAldR (mutant)+NADP+inhibitor for diabetic treatment<br /> | ||
| - | **[[1az2]] - hAldR (mutant)+NADP+citrate<br /> | + | **[[1az2]], [[6t27]], [[6t5g]], [[6y03]] - hAldR (mutant)+NADP+citrate<br /> |
| - | **[[3lbo]], [[3ld5]], [[3lql]], [[3lz5]], [[2pdc]], [[3lep]], [[3lqg]], [[3lz3]], [[3m4h]], [[2pdj]], [[2pdp]], [[2pdu]], [[3m64]], [[3mc5]] - hAldR (mutant)+IDD inhibitors<br /> | + | **[[3lbo]], [[3ld5]], [[3lql]], [[3lz5]], [[2pdc]], [[3lep]], [[3lqg]], [[3lz3]], [[3m4h]], [[2pdj]], [[2pdp]], [[2pdu]], [[3m64]], [[3mc5]], [[6t3p]], [[6t7q]], [[6td8]], [[6txp]], [[6xum]], [[6y1p]] - hAldR (mutant)+IDD inhibitors<br /> |
**[[3dn5]] – hAldR+NADP+biaryl inhibitor<br /> | **[[3dn5]] – hAldR+NADP+biaryl inhibitor<br /> | ||
**[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br /> | **[[3rx2]], [[3rx3]], [[3rx4]], [[3s3g]] - hAldR+NADP+ sulindac inhibitor<br /> | ||
**[[4igs]] - hAldR+NADP+ polyfluorinated inhibitor<br /> | **[[4igs]] - hAldR+NADP+ polyfluorinated inhibitor<br /> | ||
| - | **[[4lau]], [[4laz]], [[4lb3]], [[4lb4]], [[4lbr]], [[4lbs]], [[4qxi]] - hAldR+NADP+ carbamoyl inhibitor<br /> | + | **[[4lau]], [[4laz]], [[4lb3]], [[4lb4]], [[4lbr]], [[4lbs]], [[4qxi]], [[6syw]], [[6tuc]], [[6tuf]] - hAldR+NADP+ carbamoyl inhibitor<br /> |
**[[4qx4]] - hAldR+NADP+ mercaptotriazinoindole inhibitor<br /> | **[[4qx4]] - hAldR+NADP+ mercaptotriazinoindole inhibitor<br /> | ||
**[[3fx4]] – pAldR+NADP+thiazolidine derivative <br /> | **[[3fx4]] – pAldR+NADP+thiazolidine derivative <br /> | ||
Current revision
3D Structures of Aldose Reductase
Updated on 14-March-2021
