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2hiv

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==ATP-dependent DNA ligase from S. solfataricus==
==ATP-dependent DNA ligase from S. solfataricus==
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<StructureSection load='2hiv' size='340' side='right' caption='[[2hiv]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='2hiv' size='340' side='right'caption='[[2hiv]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2hiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2hiv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HIV FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hii|2hii]], [[2hik|2hik]], [[2hix|2hix]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hii|2hii]], [[2hik|2hik]], [[2hix|2hix]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lig ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lig ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hiv OCA], [http://pdbe.org/2hiv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hiv RCSB], [http://www.ebi.ac.uk/pdbsum/2hiv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hiv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hiv OCA], [https://pdbe.org/2hiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hiv RCSB], [https://www.ebi.ac.uk/pdbsum/2hiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hiv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DNLI_SULSO DNLI_SULSO]] DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Interaction with PCNA enhances ligase activity.[HAMAP-Rule:MF_00407]
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[[https://www.uniprot.org/uniprot/DNLI_SULSO DNLI_SULSO]] DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Interaction with PCNA enhances ligase activity.[HAMAP-Rule:MF_00407]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/2hiv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/2hiv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2hiv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2hiv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DNA ligase 3D structures|DNA ligase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Atcc 35091]]
[[Category: Atcc 35091]]
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[[Category: Large Structures]]
[[Category: Ellenberger, T]]
[[Category: Ellenberger, T]]
[[Category: Pascal, J M]]
[[Category: Pascal, J M]]

Revision as of 07:41, 17 March 2021

ATP-dependent DNA ligase from S. solfataricus

PDB ID 2hiv

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