This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2hj0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:41, 17 March 2021) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2hj0.gif|left|200px]]<br /><applet load="2hj0" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2hj0, resolution 2.70&Aring;" />
 
-
'''Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 (CASP Target).'''<br />
 
-
==About this Structure==
+
==Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 .==
-
2HJ0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans] with <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Citrate_(pro-3S)-lyase Citrate (pro-3S)-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.6 4.1.3.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJ0 OCA].
+
<StructureSection load='2hj0' size='340' side='right'caption='[[2hj0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
[[Category: Citrate (pro-3S)-lyase]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2hj0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Strmu Strmu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HJ0 FirstGlance]. <br>
-
[[Category: Streptococcus mutans]]
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
-
[[Category: Acton, T B.]]
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
[[Category: Baran, M.]]
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cilA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210007 STRMU])</td></tr>
-
[[Category: Cunningham, K.]]
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Citrate_(pro-3S)-lyase Citrate (pro-3S)-lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.6 4.1.3.6] </span></td></tr>
-
[[Category: Forouhar, F.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hj0 OCA], [https://pdbe.org/2hj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2hj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hj0 ProSAT], [https://www.topsan.org/Proteins/NESGC/2hj0 TOPSAN]</span></td></tr>
-
[[Category: Hunt, J F.]]
+
</table>
-
[[Category: Hussain, M.]]
+
== Evolutionary Conservation ==
-
[[Category: Janjua, H.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Jayaraman, S.]]
+
Check<jmol>
-
[[Category: Liu, J.]]
+
<jmolCheckbox>
-
[[Category: Ma, L C.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/2hj0_consurf.spt"</scriptWhenChecked>
-
[[Category: Montelione, G T.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: NESG, Northeast Structural Genomics Consortium.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Rost, B.]]
+
</jmolCheckbox>
-
[[Category: Shastry, R.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hj0 ConSurf].
-
[[Category: Tong, L.]]
+
<div style="clear:both"></div>
-
[[Category: Xiao, R.]]
+
__TOC__
-
[[Category: CIT]]
+
</StructureSection>
-
[[Category: alpha beta protein.]]
+
[[Category: Large Structures]]
-
[[Category: nesg]]
+
[[Category: Strmu]]
-
[[Category: northeast structural genomics consortium]]
+
[[Category: Acton, T B]]
-
[[Category: protein structure initiative]]
+
[[Category: Baran, M]]
-
[[Category: psi-2]]
+
[[Category: Cunningham, K]]
-
[[Category: structural genomics]]
+
[[Category: Forouhar, F]]
-
 
+
[[Category: Hunt, J F]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:42:29 2008''
+
[[Category: Hussain, M]]
 +
[[Category: Janjua, H]]
 +
[[Category: Jayaraman, S]]
 +
[[Category: Liu, J]]
 +
[[Category: Ma, L C]]
 +
[[Category: Montelione, G T]]
 +
[[Category: Structural genomic]]
 +
[[Category: Rost, B]]
 +
[[Category: Shastry, R]]
 +
[[Category: Tong, L]]
 +
[[Category: Xiao, R]]
 +
[[Category: Alpha beta protein]]
 +
[[Category: Lyase]]
 +
[[Category: Nesg]]
 +
[[Category: PSI, Protein structure initiative]]

Current revision

Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 .

PDB ID 2hj0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools