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1f9r
From Proteopedia
(Difference between revisions)
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<StructureSection load='1f9r' size='340' side='right'caption='[[1f9r]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1f9r' size='340' side='right'caption='[[1f9r]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1f9r]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1f9r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F9R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F9R FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1f9q|1f9q]], [[1f9s|1f9s]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1f9q|1f9q]], [[1f9s|1f9s]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f9r OCA], [https://pdbe.org/1f9r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f9r RCSB], [https://www.ebi.ac.uk/pdbsum/1f9r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f9r ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PLF4_HUMAN PLF4_HUMAN]] Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.<ref>PMID:7644496</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:02, 24 March 2021
CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 1
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