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1g9p

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<StructureSection load='1g9p' size='340' side='right'caption='[[1g9p]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1g9p' size='340' side='right'caption='[[1g9p]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1g9p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hadronyche_versuta Hadronyche versuta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G9P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1G9P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1g9p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hadronyche_versuta Hadronyche versuta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G9P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G9P FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g9p OCA], [http://pdbe.org/1g9p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1g9p RCSB], [http://www.ebi.ac.uk/pdbsum/1g9p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1g9p ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g9p OCA], [https://pdbe.org/1g9p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g9p RCSB], [https://www.ebi.ac.uk/pdbsum/1g9p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g9p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE]] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>
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[[https://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE]] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 07:13, 24 March 2021

SOLUTION STRUCTURE OF THE INSECTICIDAL CALCIUM CHANNEL BLOCKER OMEGA-ATRACOTOXIN-HV2A

PDB ID 1g9p

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