2i2o
From Proteopedia
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| - | [[Image:2i2o.gif|left|200px]] | ||
| - | + | ==Crystal Structure of an eIF4G-like Protein from Danio rerio== | |
| - | + | <StructureSection load='2i2o' size='340' side='right'caption='[[2i2o]], [[Resolution|resolution]] 1.92Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2i2o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I2O FirstGlance]. <br> | |
| - | | | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> |
| - | | | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dr.38751 (BC090306) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i2o OCA], [https://pdbe.org/2i2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i2o RCSB], [https://www.ebi.ac.uk/pdbsum/2i2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i2o ProSAT], [https://www.topsan.org/Proteins/CESG/2i2o TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [[https://www.uniprot.org/uniprot/M4GDB_DANRE M4GDB_DANRE]] Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation (By similarity). | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | == | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/2i2o_consurf.spt"</scriptWhenChecked> | |
| - | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: Bingman, C A | + | </jmolCheckbox> |
| - | [[Category: Bitto, E | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i2o ConSurf]. |
| - | [[Category: | + | <div style="clear:both"></div> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Wesenberg, G E | + | [[Category: Brachidanio rerio]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Bingman, C A]] |
| - | + | [[Category: Bitto, E]] | |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Mccoy, J G]] |
| - | + | [[Category: Phillips, G N]] | |
| - | + | [[Category: Wesenberg, G E]] | |
| + | [[Category: Cesg]] | ||
| + | [[Category: Eif4g-like protein]] | ||
| + | [[Category: PSI, Protein structure initiative]] | ||
| + | [[Category: Unknown function]] | ||
Current revision
Crystal Structure of an eIF4G-like Protein from Danio rerio
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