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2i5e
From Proteopedia
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| - | [[Image:2i5e.gif|left|200px]] | ||
| - | + | ==Crystal Structure of a Protein of Unknown Function MM2497 from Methanosarcina mazei Go1, Probable Nucleotidyltransferase== | |
| - | + | <StructureSection load='2i5e' size='340' side='right'caption='[[2i5e]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2i5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metma Metma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I5E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Methanosarcina mazei ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192952 METMA])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i5e OCA], [https://pdbe.org/2i5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i5e RCSB], [https://www.ebi.ac.uk/pdbsum/2i5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i5e ProSAT], [https://www.topsan.org/Proteins/MCSG/2i5e TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [[https://www.uniprot.org/uniprot/COFC_METMA COFC_METMA]] Guanylyltransferase that catalyzes the activation of 2-phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.[HAMAP-Rule:MF_02114] | |
| - | == | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | [[ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | [[Category: Clancy, S | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/2i5e_consurf.spt"</scriptWhenChecked> |
| - | [[Category: Du, J | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: Joachimiak, A | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: | + | </jmolCheckbox> |
| - | [[Category: Tan, K | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i5e ConSurf]. |
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Metma]] | ||
| + | [[Category: Clancy, S]] | ||
| + | [[Category: Du, J]] | ||
| + | [[Category: Joachimiak, A]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Tan, K]] | ||
[[Category: Apc86122]] | [[Category: Apc86122]] | ||
[[Category: Hypothetic protein]] | [[Category: Hypothetic protein]] | ||
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
[[Category: Methanosarcina mazei go1]] | [[Category: Methanosarcina mazei go1]] | ||
| - | [[Category: | + | [[Category: PSI, Protein structure initiative]] |
| - | + | [[Category: Unknown function]] | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of a Protein of Unknown Function MM2497 from Methanosarcina mazei Go1, Probable Nucleotidyltransferase
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