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2i5t
From Proteopedia
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| - | [[Image:2i5t.png|left|200px]] | ||
| - | + | ==Crystal Structure of hypothetical protein LOC79017 from Homo sapiens== | |
| - | + | <StructureSection load='2i5t' size='340' side='right'caption='[[2i5t]], [[Resolution|resolution]] 2.01Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2i5t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I5T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C7orf24 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i5t OCA], [https://pdbe.org/2i5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i5t RCSB], [https://www.ebi.ac.uk/pdbsum/2i5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i5t ProSAT], [https://www.topsan.org/Proteins/CESG/2i5t TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [[https://www.uniprot.org/uniprot/GGCT_HUMAN GGCT_HUMAN]] Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.<ref>PMID:16765912</ref> <ref>PMID:18515354</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[2i5t]] is a 2 chain structure with sequence from [ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | == | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/2i5t_consurf.spt"</scriptWhenChecked> |
| - | < | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: Bae, E | + | </jmolCheckbox> |
| - | [[Category: Bingman, C A | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i5t ConSurf]. |
| - | [[Category: Bitto, E | + | <div style="clear:both"></div> |
| - | [[Category: | + | == References == |
| - | [[Category: Phillips, G N | + | <references/> |
| - | [[Category: Wesenberg, G E | + | __TOC__ |
| - | + | </StructureSection> | |
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bae, E]] | ||
| + | [[Category: Bingman, C A]] | ||
| + | [[Category: Bitto, E]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Phillips, G N]] | ||
| + | [[Category: Wesenberg, G E]] | ||
[[Category: Cesg]] | [[Category: Cesg]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
| - | + | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Current revision
Crystal Structure of hypothetical protein LOC79017 from Homo sapiens
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