This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6elg
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetonitrile== | |
| - | + | <StructureSection load='6elg' size='340' side='right'caption='[[6elg]], [[Resolution|resolution]] 1.38Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6elg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ELG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ELG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3BO:1H-indol-3-ylacetonitrile'>3BO</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6ejw|6ejw]], [[6ejz|6ejz]], [[6eni|6eni]], [[6ekp|6ekp]], [[6enn|6enn]], [[6elb|6elb]], [[6elf|6elf]]</div></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6elg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6elg OCA], [https://pdbe.org/6elg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6elg RCSB], [https://www.ebi.ac.uk/pdbsum/6elg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6elg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus coli migula 1895]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Herud-Sikimic, O]] | ||
[[Category: Hocker, B]] | [[Category: Hocker, B]] | ||
| + | [[Category: Juergens, G]] | ||
[[Category: Shanmugaratnam, S]] | [[Category: Shanmugaratnam, S]] | ||
| - | [[Category: | + | [[Category: Stiel, A C]] |
| - | [[Category: | + | [[Category: Ligand binding]] |
| - | [[Category: | + | [[Category: Transcription]] |
Current revision
Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetonitrile
| |||||||||||
