This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2jyb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==binary hvDHFR1:folate complex== | ==binary hvDHFR1:folate complex== | ||
| - | <StructureSection load='2jyb' size='340' side='right' caption='[[2jyb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2jyb' size='340' side='right'caption='[[2jyb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2jyb]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2jyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_29605 Atcc 29605]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JYB FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folA ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2246 ATCC 29605])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jyb OCA], [https://pdbe.org/2jyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jyb RCSB], [https://www.ebi.ac.uk/pdbsum/2jyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jyb ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DYR_HALVD DYR_HALVD]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 31: | Line 31: | ||
==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
| Line 38: | Line 38: | ||
[[Category: Atcc 29605]] | [[Category: Atcc 29605]] | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Boroujerdi, A A.F B]] | [[Category: Boroujerdi, A A.F B]] | ||
[[Category: Young, J K]] | [[Category: Young, J K]] | ||
Revision as of 08:01, 7 April 2021
binary hvDHFR1:folate complex
| |||||||||||

