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2k74
From Proteopedia
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==Solution NMR structure of DsbB-ubiquinone complex== | ==Solution NMR structure of DsbB-ubiquinone complex== | ||
| - | <StructureSection load='2k74' size='340' side='right' caption='[[2k74]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2k74' size='340' side='right'caption='[[2k74]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k74]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2k74]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K74 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UQ2:UBIQUINONE-2'>UQ2</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UQ2:UBIQUINONE-2'>UQ2</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hi7|2hi7]], [[2k73|2k73]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hi7|2hi7]], [[2k73|2k73]]</div></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dsbB, roxB, ycgA ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dsbB, roxB, ycgA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k74 OCA], [https://pdbe.org/2k74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k74 RCSB], [https://www.ebi.ac.uk/pdbsum/2k74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k74 ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/DSBB_ECOLI DSBB_ECOLI]] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein.<ref>PMID:8430071</ref> <ref>PMID:7688471</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/2k74_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/2k74_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k74 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2k74" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Ecoli]] |
| - | [[Category: Beckwith, J | + | [[Category: Large Structures]] |
| - | [[Category: Bushweller, J H | + | [[Category: Beckwith, J]] |
| - | [[Category: Cafiso, D S | + | [[Category: Bushweller, J H]] |
| - | [[Category: Cierpicki, T | + | [[Category: Cafiso, D S]] |
| - | [[Category: Ellena, J F | + | [[Category: Cierpicki, T]] |
| - | [[Category: Jimenez, R H.Flores | + | [[Category: Ellena, J F]] |
| - | [[Category: Kadokura, H | + | [[Category: Jimenez, R H.Flores]] |
| - | [[Category: Lukasik, S M | + | [[Category: Kadokura, H]] |
| - | [[Category: Zhou, Y | + | [[Category: Lukasik, S M]] |
| + | [[Category: Zhou, Y]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
Current revision
Solution NMR structure of DsbB-ubiquinone complex
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Categories: Ecoli | Large Structures | Beckwith, J | Bushweller, J H | Cafiso, D S | Cierpicki, T | Ellena, J F | Jimenez, R H.Flores | Kadokura, H | Lukasik, S M | Zhou, Y | Chaperone | Disulfide bond | Dsbb | Electron transport | Inner membrane | Membrane protein | Oxidative protein folding | Oxidoreductase | Redox enzyme | Redox-active center | Transmembrane | Transport | Ubiquinone
