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Calmodulin

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== Calmodulin in Motion ==
== Calmodulin in Motion ==
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<jmol>
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<jmolButton>
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<script>
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script "/wiki/images/1/1a/Morph.spt";
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load files "=1prw" "=1cll";
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delete water;
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delete protein and not alpha;
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model 1;
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display 4-138
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center visible;
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backbone only;
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backbone 0.5;
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color group;
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compare {2.1} {1.1} SUBSET{*.CA} ATOMS{4-138}{4-138} ROTATE TRANSLATE;
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</script>
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<text>Prepare Animation</text>
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</jmolButton>
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</jmol><jmol>
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<jmolButton>
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<script>
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structures = [{1.1}, {2.1}];
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my_recipe = [
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[0, 1, 0, {79-147},{79-147}, {(79-138) and alpha}, 0],
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[0, 1, 0, {8-78}, {79}, {(4-78) and alpha}, 0],
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];
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morph(20, structures, my_recipe, 0);
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</script>
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<text>Run morph</text>
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</jmolButton>
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</jmol>
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The clip represents Calmodulin in motion. At the beginning it is shown moving in the unbound form (ApoCaM), and it changes its conformation when Calcium ions are present in the medium (CaCaM).
The clip represents Calmodulin in motion. At the beginning it is shown moving in the unbound form (ApoCaM), and it changes its conformation when Calcium ions are present in the medium (CaCaM).

Revision as of 21:03, 10 April 2021

Human calmodulin complex with ethanol and Ca+2 ions (green) (PDB code 1cll)

Drag the structure with the mouse to rotate

See Also

Bibliography

  1. ↑ Chattopadhyaya R, Meador WE, Means AR, Quiocho FA. Calmodulin structure refined at 1.7 A resolution. J Mol Biol. 1992 Dec 20;228(4):1177-92. PMID:1474585
  2. ↑ Bertini I, Giachetti A, Luchinat C, Parigi G, Petoukhov MV, Pierattelli R, Ravera E, Svergun DI. Conformational Space of Flexible Biological Macromolecules from Average Data. J Am Chem Soc. 2010 Sep 7. PMID:20822180 doi:10.1021/ja1063923
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