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2kki
From Proteopedia
(Difference between revisions)
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==Solution structure of human Interleukin 1a== | ==Solution structure of human Interleukin 1a== | ||
| - | <StructureSection load='2kki' size='340' side='right' caption='[[2kki]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''> | + | <StructureSection load='2kki' size='340' side='right'caption='[[2kki]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kki]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kki]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KKI FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL1A, IL1F1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL1A, IL1F1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kki OCA], [https://pdbe.org/2kki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kki RCSB], [https://www.ebi.ac.uk/pdbsum/2kki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kki ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/IL1A_HUMAN IL1A_HUMAN]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Interleukin|Interleukin]] | + | *[[Interleukin 3D structures|Interleukin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Chang, H K]] | [[Category: Chang, H K]] | ||
[[Category: Mohan, S K]] | [[Category: Mohan, S K]] | ||
Revision as of 07:27, 14 April 2021
Solution structure of human Interleukin 1a
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Categories: Human | Large Structures | Chang, H K | Mohan, S K | Yu, C | Cytokine | Glycoprotein | Inflammatory response | Lipoprotein | Mitogen | Myristate | Polymorphism | Protein | Pyrogen | Secreted
