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1nfh

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<StructureSection load='1nfh' size='340' side='right'caption='[[1nfh]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='1nfh' size='340' side='right'caption='[[1nfh]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1nfh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NFH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1nfh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NFH FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nfh OCA], [http://pdbe.org/1nfh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nfh RCSB], [http://www.ebi.ac.uk/pdbsum/1nfh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nfh ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nfh OCA], [https://pdbe.org/1nfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nfh RCSB], [https://www.ebi.ac.uk/pdbsum/1nfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nfh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ALBA2_ARCFU ALBA2_ARCFU]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).[HAMAP-Rule:MF_01122]
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[[https://www.uniprot.org/uniprot/ALBA2_ARCFU ALBA2_ARCFU]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).[HAMAP-Rule:MF_01122]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 09:34, 5 May 2021

Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding

PDB ID 1nfh

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