Beta secretase 3D structures
From Proteopedia
(Difference between revisions)
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**[[3fkt]] – hBACE-1 catalytic domain (mutant) + aminohydantoin inhibitor<br /> | **[[3fkt]] – hBACE-1 catalytic domain (mutant) + aminohydantoin inhibitor<br /> | ||
**[[3k5c]], [[3l58]], [[3l59]], [[3l5b]], [[3l5c]], [[3l5d]], [[3l5e]], [[3l5f]], [[3duy]], [[3dv1]], [[3dv5]], [[2f3e]], [[2f3f]], [[1ym2]], [[1ym4]], [[3skf]], [[3skg]], [[4h1e]], [[4h3j]], [[4ha5]], [[4gmi]], [[4k8s]], [[4k9h]], [[6nv7]], [[6nv9]], [[6nw3]] – hBACE-1 catalytic domain+ macrocyclic inhibitor<br /> | **[[3k5c]], [[3l58]], [[3l59]], [[3l5b]], [[3l5c]], [[3l5d]], [[3l5e]], [[3l5f]], [[3duy]], [[3dv1]], [[3dv5]], [[2f3e]], [[2f3f]], [[1ym2]], [[1ym4]], [[3skf]], [[3skg]], [[4h1e]], [[4h3j]], [[4ha5]], [[4gmi]], [[4k8s]], [[4k9h]], [[6nv7]], [[6nv9]], [[6nw3]] – hBACE-1 catalytic domain+ macrocyclic inhibitor<br /> | ||
| - | **[[3ckp]], [[3ckr]], [[2qzk]], [[2ph8]], [[2va5]], [[2va6]], [[2va7]], [[2ph6]], [[4ke0]], [[4ke1]] – hBACE-1 catalytic domain (mutant) + macrocyclic inhibitor<br /> | + | **[[3ckp]], [[3ckr]], [[2qzk]], [[2ph8]], [[2va5]], [[2va6]], [[2va7]], [[2ph6]], [[4ke0]], [[4ke1]], [[6uj1]] – hBACE-1 catalytic domain (mutant) + macrocyclic inhibitor<br /> |
**[[3ohh]], [[3ohf]], [[3n4l]], [[3nsh]], [[2iqg]], [[3pi5]], [[3qbh]], [[4dpf]], [[4dpi]], [[4dus]], [[4fs4]], [[4ewo]], [[4exg]], [[3veu]], [[3vf3]], [[3vg1]], [[4d83]], [[4d85]], [[4d88]]], [[4d89]], [[4d8c]], [[3qi1]], [[4lxa]], [[4lxk]], [[4lxm]] – hBACE-1 catalytic domain+ hydroxyethylamine inhibitor<br /> | **[[3ohh]], [[3ohf]], [[3n4l]], [[3nsh]], [[2iqg]], [[3pi5]], [[3qbh]], [[4dpf]], [[4dpi]], [[4dus]], [[4fs4]], [[4ewo]], [[4exg]], [[3veu]], [[3vf3]], [[3vg1]], [[4d83]], [[4d85]], [[4d88]]], [[4d89]], [[4d8c]], [[3qi1]], [[4lxa]], [[4lxk]], [[4lxm]] – hBACE-1 catalytic domain+ hydroxyethylamine inhibitor<br /> | ||
**[[3i25]] – hBACE-1 catalytic domain+ hydroxyethylene inhibitor<br /> | **[[3i25]] – hBACE-1 catalytic domain+ hydroxyethylene inhibitor<br /> | ||
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**[[2q11]], [[2q15]], [[4i0e]], [[4i0f]], [[4i0g]], [[4i10]], [[4i11]], [[4i12]], [[4i1c]], [[5mxd]], [[2wjo]] – hBACE-1 catalytic domain+ quinazoline inhibitor<br /> | **[[2q11]], [[2q15]], [[4i0e]], [[4i0f]], [[4i0g]], [[4i10]], [[4i11]], [[4i12]], [[4i1c]], [[5mxd]], [[2wjo]] – hBACE-1 catalytic domain+ quinazoline inhibitor<br /> | ||
**[[2vnm]], [[2vnn]], [[2vie]], [[2vij]], [[2viy]], [[2viz]], [[2vj6]], [[2vj7]], [[2vj9]], [[4dh6]], [[4di2]] – hBACE-1 catalytic domain (mutant) + hydroxyethylamine inhibitor<br /> | **[[2vnm]], [[2vnn]], [[2vie]], [[2vij]], [[2viy]], [[2viz]], [[2vj6]], [[2vj7]], [[2vj9]], [[4dh6]], [[4di2]] – hBACE-1 catalytic domain (mutant) + hydroxyethylamine inhibitor<br /> | ||
| - | **[[4b78]], [[3l38]], [[3l3a]], [[6eqm]], [[6dmi]], [[6e3z]], [[6jsg]], [[6uvp]] – hBACE-1 catalytic domain + pyridine inhibitor<br /> | + | **[[4b78]], [[3l38]], [[3l3a]], [[6eqm]], [[6dmi]], [[6e3z]], [[6jsg]], [[6uvp]], [[7b1e]], [[7b1p]], [[7b1q]], [[7d2v]], [[7d2x]], [[7d5a]], [[7dcz]] – hBACE-1 catalytic domain + pyridine inhibitor<br /> |
**[[2ohq]], [[2ohr]], [[2ohs]], [[2oht]], [[2ohu]], [[2ohp]], [[4j0p]], [[2ntr]], [[2ohm]], [[4azy]], [[4b00]], [[4b05]], [[3zmg]], [[4j0t]], [[4j0v]], [[4j0y]], [[4j0z]], [[4j1i]], [[4j1k]], [[3zov]], [[4bfd]] – hBACE-1 catalytic domain (mutant) + pyridine inhibitor<br /> | **[[2ohq]], [[2ohr]], [[2ohs]], [[2oht]], [[2ohu]], [[2ohp]], [[4j0p]], [[2ntr]], [[2ohm]], [[4azy]], [[4b00]], [[4b05]], [[3zmg]], [[4j0t]], [[4j0v]], [[4j0y]], [[4j0z]], [[4j1i]], [[4j1k]], [[3zov]], [[4bfd]] – hBACE-1 catalytic domain (mutant) + pyridine inhibitor<br /> | ||
**[[2b8v]], [[2irz]], [[2xfi]], [[2xfj]], [[2xfk]], [[1w51]] – hBACE-1 catalytic domain (mutant) + benzamide inhibitor<br /> | **[[2b8v]], [[2irz]], [[2xfi]], [[2xfj]], [[2xfk]], [[1w51]] – hBACE-1 catalytic domain (mutant) + benzamide inhibitor<br /> | ||
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**[[4acx]] – hBACE-1 catalytic domain (mutant) + aminoimidazole inhibitor<br /> | **[[4acx]] – hBACE-1 catalytic domain (mutant) + aminoimidazole inhibitor<br /> | ||
**[[2zhr]], [[1xn2]], [[1xn3]], [[1m4h]], [[1fkn]], [[5mcq]] - hBACE-1 catalytic domain + peptide inhibitor<br /> | **[[2zhr]], [[1xn2]], [[1xn3]], [[1m4h]], [[1fkn]], [[5mcq]] - hBACE-1 catalytic domain + peptide inhibitor<br /> | ||
| - | **[[5mbw]], [[5mco]] - hBACE-1 catalytic domain (mutant) + peptide inhibitor<br /> | + | **[[5mbw]], [[5mco]], [[6uj0]] - hBACE-1 catalytic domain (mutant) + peptide inhibitor<br /> |
**[[6wny]] – hBACE-1 catalytic domain + fluoro-olefin inhibitor<br /> | **[[6wny]] – hBACE-1 catalytic domain + fluoro-olefin inhibitor<br /> | ||
**[[2oah]], [[1tqf]], [[3uqp]], [[3uqr]], [[3uqu]], [[3uqw]], [[3uqx]], [[4fgx]] - hBACE-1 catalytic domain (mutant)+inhibitor<br /> | **[[2oah]], [[1tqf]], [[3uqp]], [[3uqr]], [[3uqu]], [[3uqw]], [[3uqx]], [[4fgx]] - hBACE-1 catalytic domain (mutant)+inhibitor<br /> | ||
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**[[3zkm]], [[3zkn]] - hBACE-2 extracellular domain + FAB<br /> | **[[3zkm]], [[3zkn]] - hBACE-2 extracellular domain + FAB<br /> | ||
**[[3zkq]], [[3zks]], [[3zkx]], [[4bel]], [[4bfb]] - hBACE-2 extracellular domain + xaperon<br /> | **[[3zkq]], [[3zks]], [[3zkx]], [[4bel]], [[4bfb]] - hBACE-2 extracellular domain + xaperon<br /> | ||
| - | **[[6jsz]] - hBACE-2 extracellular domain + xaperon + pyrazine inhibitor<br /> | + | **[[6jsz]], [[7d5b]], [[7d5u]] - hBACE-2 extracellular domain + xaperon + pyrazine inhibitor<br /> |
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:46, 12 May 2021
3D Structures of Beta secretase
Updated on 12-May-2021
