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1oia
From Proteopedia
(Difference between revisions)
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<StructureSection load='1oia' size='340' side='right'caption='[[1oia]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='1oia' size='340' side='right'caption='[[1oia]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1oia]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1oia]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1nrc 1nrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OIA FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aud|1aud]], [[1cx0|1cx0]], [[1drz|1drz]], [[1dz5|1dz5]], [[1fht|1fht]], [[1m5k|1m5k]], [[1m5o|1m5o]], [[1m5p|1m5p]], [[1m5v|1m5v]], [[1nu4|1nu4]], [[1urn|1urn]], [[2u1a|2u1a]], [[3utr|3utr]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aud|1aud]], [[1cx0|1cx0]], [[1drz|1drz]], [[1dz5|1dz5]], [[1fht|1fht]], [[1m5k|1m5k]], [[1m5o|1m5o]], [[1m5p|1m5p]], [[1m5v|1m5v]], [[1nu4|1nu4]], [[1urn|1urn]], [[2u1a|2u1a]], [[3utr|3utr]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oia OCA], [https://pdbe.org/1oia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oia RCSB], [https://www.ebi.ac.uk/pdbsum/1oia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oia ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN]] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Nucleoprotein|Nucleoprotein]] | + | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 09:57, 12 May 2021
U1A rnp domain 1-95
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