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4qkj

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==Glycosylated form of human LLT1, a ligand for NKR-P1, in this structure forming hexamers==
==Glycosylated form of human LLT1, a ligand for NKR-P1, in this structure forming hexamers==
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<StructureSection load='4qkj' size='340' side='right' caption='[[4qkj]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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<StructureSection load='4qkj' size='340' side='right'caption='[[4qkj]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qkj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QKJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QKJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qkg|4qkg]], [[4qkh|4qkh]], [[4qki|4qki]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4qkg|4qkg]], [[4qkh|4qkh]], [[4qki|4qki]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLAX, CLEC2B, CLEC2D, LLT1, OCIL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLAX, CLEC2B, CLEC2D, LLT1, OCIL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qkj OCA], [http://pdbe.org/4qkj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qkj RCSB], [http://www.ebi.ac.uk/pdbsum/4qkj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qkj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qkj OCA], [https://pdbe.org/4qkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qkj RCSB], [https://www.ebi.ac.uk/pdbsum/4qkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qkj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CLC2D_HUMAN CLC2D_HUMAN]] Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.<ref>PMID:14753741</ref> <ref>PMID:15104121</ref> <ref>PMID:16339513</ref>
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[[https://www.uniprot.org/uniprot/CLC2D_HUMAN CLC2D_HUMAN]] Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.<ref>PMID:14753741</ref> <ref>PMID:15104121</ref> <ref>PMID:16339513</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Blaha, J]]
[[Category: Blaha, J]]
[[Category: Dohnalek, J]]
[[Category: Dohnalek, J]]

Revision as of 14:40, 2 June 2021

Glycosylated form of human LLT1, a ligand for NKR-P1, in this structure forming hexamers

PDB ID 4qkj

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